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Clog mitigation in a microfluidic array via pulsatile flows.

Brian Dincau1, Connor Tang1, Emilie Dressaire1

  • 1Department of Mechanical Engineering, University of California, Santa Barbara, California 93106, USA. dressaire@ucsb.edu.

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|January 26, 2022
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Summary
This summary is machine-generated.

Pulsatile flows effectively mitigate clogging in microfluidic filters by rearranging particles, enhancing throughput. However, this benefit diminishes at lower frequencies due to timescale mismatches with filter cake growth.

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Area of Science:

  • Fluid Dynamics
  • Colloid Science
  • Microfluidics

Background:

  • Clogging in microfluidic systems poses significant challenges in various applications.
  • Pulsatile flows offer a potential solution to mitigate clogging compared to steady flows.

Purpose of the Study:

  • To experimentally investigate the impact of pulsatile flow parameters on clog mitigation.
  • To analyze the influence of pulsation amplitude and frequency on filter performance.

Main Methods:

  • Utilized a microfluidic array of parallel channels with colloidal suspensions.
  • Performed flow rate measurements and direct pore-scale visualizations.
  • Varied pulsation amplitude (0.25P₀ to 1.25P₀) and frequency (10⁻³ Hz to 10⁻¹ Hz).

Main Results:

  • Pulsatile flows at 0.1 Hz significantly increased throughput compared to steady flows.
  • Particle rearrangement under dynamic shear delayed or removed clogs.
  • Benefits of pulsatile flow were reduced at 10⁻² Hz and absent at 10⁻³ Hz.

Conclusions:

  • Pulsatile flows are a promising strategy for delaying clogging at both pore and system levels.
  • Optimal pulsation frequencies are crucial for effective clog mitigation.
  • Understanding timescale dynamics is key to maximizing the benefits of pulsatile flows.