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Science Translation During the COVID-19 Pandemic: An Academic-Public Health Partnership to Assess Capacity Limits in
Peter Maldonado1, Angie Peng1, Derek Ouyang1
1Peter Maldonado is with the Department of Computer Science and the Regulation, Evaluation, and Governance Lab (RegLab), Stanford University, Stanford, CA. Angie Peng is with the Department of Management Science and Engineering, School of Engineering, Stanford University. Derek Ouyang is with the Future Bay Initiative and the RegLab, Stanford University. Jenny Suckale is with the Department of Geophysics at Stanford Earth, School of Earth, Energy, and Environmental Sciences, and the Future Bay Initiative, Stanford University. Daniel E. Ho is with Stanford Law School, Department of Political Science, School of Humanities and Sciences, the Stanford Institute for Economic Policy Research, the Stanford Institute for Human-Centered Artificial Intelligence, and the RegLab, Stanford University.
Abstract:
On the basis of an extensive academic-public health partnership around COVID-19 response, we illustrate the challenge of science-policy translation by examining one of the most common nonpharmaceutical interventions: capacity limits. We study the implementation of a 20% capacity limit in retail facilities in the California Bay Area. Through a difference-in-differences analysis, we show that the intervention caused no material reduction in visits, using the same large-scale mobile device data on human movements (mobility data) originally used in the academic literature to support such limits. We show that the lack of effectiveness stems from a mismatch between the academic metric of capacity relative to peak visits and the policy metric of capacity relative to building code. The disconnect in metrics is amplified by mobility data losing predictive power after the early months of the pandemic, weakening the policy relevance of mobility-based interventions. Nonetheless, the data suggest that a better-grounded rationale for capacity limits is to reduce risk specifically during peak hours. To enhance the connection between science, policy, and public health in future times of crisis, we spell out 3 strategies: living models, coproduction, and shared metrics. (Am J Public Health. 2022;112(2):308-315. https://doi.org/10.2105/AJPH.2021.306576).
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Translation
Translation is the process of synthesizing proteins from the genetic information carried by messenger RNA (mRNA). Following transcription, it constitutes the final step in the expression of genes. This process is carried out by ribosomes, complexes of protein and specialized RNA molecules. Ribosomes, transfer RNA (tRNA), and other proteins produce a chain of amino acids—the polypeptide—as the end product of translation.
Translation Produces the Building Blocks of...

