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The neutralization of hydroxyl radical by silibin, sorbinil and bendazac
M L Mira1, M S Azevedo, C Manso
1Instituto de Química Fisológica, Faculdade de Medicina de Lisboa, Portugal.
Free Radical Research Communications
|January 1, 1987
Abstract:
The compounds silibin, sorbinil and bendazac act as hydroxyl radical scavengers, when the hydroxyl radical is generated by the Fenton reaction. Hydroxyl was detected by the degradation of deoxyribose. The Authors discuss the possibility that the scavenger activities of those compounds may explain, at least in part, their therapeutic activity.