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Related Experiment Video

Updated: Oct 5, 2025

Inducement and Evaluation of a Murine Model of Experimental Myopia

Inducement and Evaluation of a Murine Model of Experimental Myopia

Published on: January 22, 2019

A mysterious myopic surprise.

Nicole R Fram¹, Sahar Bedrood, Georges M Durr

¹Los Angeles, California.

Journal of Cataract and Refractive Surgery

|January 27, 2022

Summary

A patient experienced a significant myopic surprise after cataract surgery with microstent implantation. This case highlights potential complications and the need for careful diagnosis and management in glaucoma patients.

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Inducement and Evaluation of a Murine Model of Experimental Myopia

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Published on: May 26, 2023

Area of Science:

Ophthalmology
Glaucoma Surgery
Cataract Surgery

Background:

A 73-year-old male with a history of inactive age-related macular degeneration and chronic angle-closure glaucoma (CACG) underwent femtosecond laser-assisted cataract surgery with intraocular lens (IOL) implantation and simultaneous Hydrus microstent implantation in the left eye.
The patient had a history of acute angle-closure glaucoma (ACG) and complicated cataract surgery in the right eye, with a failed trabeculectomy and subsequent laser peripheral iridoplasty.

Observation:

Two months postoperatively, the patient presented with a myopic surprise of approximately 2.0 diopters in the left eye.
Examination revealed differences in visual acuity and intraocular pressure (IOP) between the eyes, with a shallow anterior chamber and iris abnormalities in the left eye.

Findings:

The myopic surprise in the left eye, post-Hydrus microstent and cataract surgery, suggests a potential complication.
Findings included a fibrotic pupillary membrane, iris transillumination defects, and lens pitting in the left eye, alongside elevated IOP.

Implications:

This case underscores the importance of considering refractive surprises after combined glaucoma and cataract surgery.
Further diagnostic evaluation and tailored management strategies are crucial for optimizing visual outcomes in complex glaucoma patients.