The Role of Ultrasonography forDiagnosing Wilms Tumor in Developing Country

Aulia Rahmani1, Nur Melani Sari2, Vita Indriasari3

  • 1Faculty of Medicine, Universitas Padjadjaran, Bandung, Indonesia.

Insights

Ultrasonography (USG) is a common initial test for pediatric abdominal masses, but this study found no significant link between USG results and histopathology in diagnosing Wilm's Tumor and other pediatric renal malignancies.

Area of Science:

  • Pediatric Oncology
  • Diagnostic Imaging
  • Pathology

Background:

  • Wilm's Tumor (WT) survival rates are low in developing nations, often due to delayed diagnosis.
  • Ultrasonography (USG) is a cost-effective, non-invasive first-line imaging tool for suspected pediatric abdominal masses, with 76% sensitivity.
  • The diagnostic accuracy of USG compared to histopathology in pediatric renal malignancies needs evaluation.

Purpose of the Study:

  • To assess the relationship between ultrasonography (USG) findings and histopathological diagnoses in pediatric renal malignancies.
  • To determine if USG can reliably predict histopathological outcomes for conditions like Wilm's Tumor.

Main Methods:

  • A cross-sectional analytical study was conducted from 2015-2018 at Dr. Hasan Sadikin Hospital.
  • Medical records of pediatric patients (0-18 years) with renal malignancy or neuroblastoma were reviewed.
  • Fisher exact test was used to analyze the association between USG and histopathology results.

Main Results:

  • The study included 43 pediatric patients: 33 with Wilm's Tumor, 6 with neuroblastoma, and 4 with other renal malignancies.
  • Fisher exact test showed no statistically significant relationship between USG findings and histopathological diagnoses (p > 0.05).

Conclusions:

  • Ultrasonography interpretation may lack a significant correlation with definitive histopathological diagnoses in pediatric renal tumors.
  • Centralized interpretation of USG in pediatric oncology may improve diagnostic consistency.

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