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Stent or Shunt, What Could be Better for Children with Duct Dependent Pulmonary Circulation?
Ghassan A Shaath1,2, Abdulraouf Mz Jijeh1,2, Mohammed Fararjeh1,2
1Department of Cardiac Sciences, King Abdulaziz Cardiac Center, Ministry of National Guard Health Affairs, Riyadh, Saudi Arabia.
Insights
Systemic to pulmonary shunt and PDA stent offer alternatives for duct-dependent pulmonary circulation. PDA stents reduce ICU stay but increase thrombosis risk, while both methods support pulmonary artery growth and survival.
Area of Science:
- Pediatric Cardiology
- Congenital Heart Disease
- Interventional Cardiology
Background:
- Systemic to pulmonary shunt (Shunt) is a common palliation for duct-dependent pulmonary circulation in children.
- Patent ductus arteriosus (PDA) stent (Stent) is an emerging alternative for augmenting pulmonary blood flow.
- Comparing outcomes between Shunt and Stent procedures is crucial for optimizing pediatric cardiac care.
Purpose of the Study:
- To compare post-intervention outcomes in children undergoing either a systemic to pulmonary shunt or a PDA stent.
- To evaluate the efficacy and safety of PDA stenting as an alternative to traditional shunting procedures.
- To analyze differences in intensive care unit (ICU) stay, ventilation, thrombotic events, and long-term growth.
Main Methods:
- Retrospective review of infants under 3 months who received either a Shunt or Stent between 2008 and 2016.
- Follow-up until the second intervention or 1 year, whichever occurred earlier.
- Comparison of clinical outcomes including ICU stay, ventilation days, thrombotic events, pulmonary artery growth, readmissions, and survival.
Main Results:
- 187 patients (110 Shunt, 77 Stent) were analyzed; initial characteristics were similar.
- Stent group had significantly shorter ICU stays (4 vs. 13 days) and ventilation days (1 vs. 5.5 days).
- Stent group experienced more thrombotic events, while both groups showed comparable pulmonary artery growth, somatic growth, and survival rates, with a trend towards lower mortality in the Stent group.
Conclusions:
- PDA stent implantation leads to a smoother ICU course and shorter hospital stay but carries a higher risk of vascular injury.
- Both Shunt and Stent procedures demonstrate favorable outcomes for pulmonary artery growth, somatic growth, and patient survival.
- The choice between Shunt and Stent should consider the trade-off between reduced ICU morbidity and increased thrombotic risk.
Background:
Systemic to pulmonary shunt (Shunt) is offered for children with duct dependent pulmonary circulation to augment pulmonary flow. Recently patent ductus arteriosus (PDA) stent (Stent) is widely used as an alternative method. We aimed to compare post intervention outcomes in children underwent either procedure.
Methods:
Infants under 3 months who had an initial palliation by Shunt or Stent were retrospectively reviewed between 2008 and 2016, then followed till the second intervention or 1 year whichever earlier.
Results:
187 patients (110 Shunt and 77 Stent) were included. Initial weight and pulmonary artery (PA) branches size were similar between the groups. Shunt patients had more shock preoperatively and required more emergency intervention. Stent group showed less ICU stay 4 (1-8) vs 13 (7-23) days, p < 0.0001 and less positive pressure ventilation days 1 (0-2) vs 5.5 (3-11), p < 0.0001. However, Stent group had more symptomatic arterial and deep venous thromboses. In Stent patients the branch PAs growth was better and more homogeneous. At follow-up, no difference between groups regarding cumulative readmission days to hospital, hemoglobin levels and the weight percentile for age. Mortality was not different with a tendency to be higher in the Shunt group (13%) compared to the Stent group (5%), p 0.1.
Conclusions:
The implantation of PDA stent in patients with duct dependent pulmonary circulation results in a smoother ICU course and a shorter hospital stay, with higher risk of vascular injury. Shunt and Stent procedures have a good outcome for PA growth, somatic growth and survival.
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