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Updated: Oct 5, 2025

Preparation, Procedures and Evaluation of Platelet-Rich Plasma Injection in the Treatment of Knee Osteoarthritis
Published on: January 4, 2019
[PRP and knee osteoarthritis]
Julie Küffer1, Jean-Luc Ziltener2
1Clinique de Genolier, 1272 Genolier.
Abstract:
Knee osteoarthritis is a common degenerative disease. The functional impact on patients can be major. Platelet-rich plasma (PRP) is a platelet concentrate obtained by centrifugation of a blood sample rich in growth factors. Once injected into the joint, they induce a natural cascade that can lead to a stimulation of the potential regenerative capacity of cartilage. The effectiveness of PRP in knee osteoarthritis is debated, but recent studies exist. The aim of this article is to provide a relatively exhaustive summary. The results of our review tend to demonstrate that intra-articular injections of PRP have an important, allowing a significant analgesic effect and functional improvement.

