Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Neural Regulation of Blood Pressure01:18

Neural Regulation of Blood Pressure

4.4K
The neural regulation of blood pressure involves intricate interactions between the autonomic nervous system (ANS) and cardiovascular system, ensuring adequate perfusion of tissues. This regulation primarily occurs through baroreceptor and chemoreceptor reflexes, involving both short-term and long-term mechanisms.
Baroreceptor Reflex
Baroreceptors, located in the carotid sinuses and aortic arch, detect changes in blood pressure. When blood pressure rises, these stretch-sensitive receptors...
4.4K
Regulation of the Cardiovascular System01:27

Regulation of the Cardiovascular System

2.1K
The regulation of the cardiovascular system allows the body to adapt to various demands and maintain homeostasis.
The regulation of the cardiovascular system involves the autonomic nervous system (ANS), baroreceptors, and chemoreceptors, ensuring that heart rate and blood pressure are appropriately modulated in response to varying physiological demands.
The ANS comprises two main divisions: the sympathetic and parasympathetic nervous systems. The sympathetic nervous system enhances...
2.1K
Physiological Foundation of Stress01:24

Physiological Foundation of Stress

198
Stress triggers a coordinated physiological response involving the sympathetic nervous system (SNS) and the hypothalamic-pituitary-adrenal (HPA) axis. This dual activation ensures that the body is prepared for both immediate and prolonged stress management. The process begins with the perception of a stressor. This initial phase activates the SNS, leading to the rapid release of adrenaline (epinephrine) from the adrenal glands.
Role of the Sympathetic Nervous System
Adrenaline triggers the...
198
Hypothalamic-Pituitary Axis01:37

Hypothalamic-Pituitary Axis

62.4K
The response to stress—be it physical or psychological, acute or chronic—involves activation of the Hypothalamic-Pituitary-Adrenal (HPA) axis. The HPA axis is part of the neuroendocrine system because it involves both neuronal and hormonal communication. Its function is to regulate homeostatic systems—metabolic, cardiovascular, and immune—providing the necessary means to respond to a stressor.
62.4K
The Sympathetic Nervous System01:25

The Sympathetic Nervous System

97.5K
Overview
97.5K
Hypertension and Regulation of Blood Pressure01:18

Hypertension and Regulation of Blood Pressure

3.3K
Hypertension, the most common cardiovascular disease, is diagnosed through repeated measurements of elevated blood pressure. Its risks, including damage to the kidney, heart, and brain, are directly proportional to blood pressure levels. Starting from 115/75 mm Hg, the risk of cardiovascular disease doubles with each increment of 20/10 mm Hg. The diagnosis relies on blood pressure measurements, not on patient symptoms, as hypertension is often asymptomatic until end-organ damage is imminent or...
3.3K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Can a neck lift trigger orthostatic hypertension and tremors?

Clinical autonomic research : official journal of the Clinical Autonomic Research Society·2026
Same author

Exploratory Analysis of ELP1 Expression in Whole Blood From Patients With Familial Dysautonomia.

Annals of clinical and translational neurology·2025
Same author

Pharmacodynamics, Safety, and Tolerability of Pyridostigmine Bromide in Heart Failure.

Current therapeutic research, clinical and experimental·2025
Same author

Establishing minimally clinically important differences for the orthostatic hypotension questionnaire (OHQ).

Clinical autonomic research : official journal of the Clinical Autonomic Research Society·2025
Same author

Genome-wide association study of REM sleep behavior disorder in Parkinson's disease.

NPJ Parkinson's disease·2025
Same author

Genetic Modifiers of Parkinson's Disease: A Case-Control Study.

Annals of clinical and translational neurology·2025

Related Experiment Video

Updated: Oct 5, 2025

Implantation of Combined Telemetric ECG and Blood Pressure Transmitters to Determine Spontaneous Baroreflex Sensitivity in Conscious Mice
09:56

Implantation of Combined Telemetric ECG and Blood Pressure Transmitters to Determine Spontaneous Baroreflex Sensitivity in Conscious Mice

Published on: February 14, 2021

5.4K

Stress and the baroreflex.

Lucy Norcliffe-Kaufmann1

  • 1Department of Neurology, New York University School of Medicine, New York, NY, USA.

Autonomic Neuroscience : Basic & Clinical
|January 27, 2022
PubMed
Summary
This summary is machine-generated.

The baroreflex normally buffers stress responses, but its loss can lead to hypertension and cardiovascular disease. Impaired baroreflex sensitivity is linked to heightened stress reactions and increased mortality.

Keywords:
AdrenalineBaroreflexBlood pressureStress

More Related Videos

An Alternative to the Traditional Cold Pressor Test: The Cold Pressor Arm Wrap
09:16

An Alternative to the Traditional Cold Pressor Test: The Cold Pressor Arm Wrap

Published on: January 16, 2014

14.6K
Restraint to Induce Stress in Mice and Rats
03:48

Restraint to Induce Stress in Mice and Rats

Published on: December 6, 2024

2.0K

Related Experiment Videos

Last Updated: Oct 5, 2025

Implantation of Combined Telemetric ECG and Blood Pressure Transmitters to Determine Spontaneous Baroreflex Sensitivity in Conscious Mice
09:56

Implantation of Combined Telemetric ECG and Blood Pressure Transmitters to Determine Spontaneous Baroreflex Sensitivity in Conscious Mice

Published on: February 14, 2021

5.4K
An Alternative to the Traditional Cold Pressor Test: The Cold Pressor Arm Wrap
09:16

An Alternative to the Traditional Cold Pressor Test: The Cold Pressor Arm Wrap

Published on: January 16, 2014

14.6K
Restraint to Induce Stress in Mice and Rats
03:48

Restraint to Induce Stress in Mice and Rats

Published on: December 6, 2024

2.0K

Area of Science:

  • Cardiovascular physiology
  • Neuroscience
  • Stress response

Background:

  • The body's stress response involves hormones like glucocorticoids and catecholamines, alongside autonomic nervous system activation.
  • The baroreflex is crucial for maintaining blood pressure homeostasis during stress.
  • Chronic or exaggerated stress responses can be detrimental, leading to conditions like hypertension.

Purpose of the Study:

  • To review how the baroreflex responds to acute and chronic stressors.
  • To examine the impact of baroreflex pathway lesions on stress response modulation.
  • To discuss methods for assessing baroreflex sensitivity and stress responses.

Main Methods:

  • Literature review of studies on baroreflex function under stress.
  • Analysis of research on neuronal pathways involved in baroreflex regulation.
  • Examination of techniques for measuring baroreflex sensitivity and autonomic activity.

Main Results:

  • Acute stressors activate autonomic responses buffered by the baroreflex.
  • Chronic stress or baroreflex impairment can lead to maladaptive cardiovascular changes.
  • Loss of baroreflex sensitivity is associated with heightened sympathetic activity during stress.

Conclusions:

  • Baroreflex dysfunction plays a significant role in the pathophysiology of stress-related cardiovascular diseases.
  • Impaired baroreflex sensitivity may contribute to the link between stress, mortality, and cardiovascular disease.
  • Understanding baroreflex mechanisms is key to managing stress-induced cardiovascular risks.