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Evaluation of mumps antibodies after measles-mumps-rubella (MMR) vaccines
K Ozaki1, H Kuno-Sakai, M Kimura
1Department of Pediatrics, School of Medicine, Tokai University, Kanagawa, Japan.
The Tokai Journal of Experimental and Clinical Medicine
|December 1, 1987
Abstract:
Mumps antibody titers before and after administration of MMR trivalent combined vaccines from 3 different company were evaluated by mumps IgG Enzyme Linked Immunosorbent Assay (ELISA) and by neutralizing antibody test (NT). Seroconversion rates determined with the ELISA were around 90% in all 3 different vaccines. The seroconversion by NT test ranged from 63% to 77%. The mumps ELISA is more sensitive method of determination of antibodies against mumps virus than NT. Since ELISA is a much simpler and easier method of determining antibodies than NT, it will be a method of choice in many clinical laboratories.