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Updated: Oct 5, 2025

Echocardiographic Approaches and Protocols for Comprehensive Phenotypic Characterization of Valvular Heart Disease in Mice
Published on: February 14, 2017
Three-dimensional echocardiographic assessment of the aortic valve and the aorta
Aiman Smer1, Prakrity Urja1, Dixitha Anugula1
1CHI-Health-Creighton University School of Medicine, Omaha, Nebraska.
Insights
Three-dimensional echocardiography (3DE) aids in evaluating the aortic valve and aorta. This technique provides detailed imaging for better assessment of these critical cardiac structures.
Area of Science:
- Cardiology
- Medical Imaging
Background:
- The aortic valve and aorta are crucial for cardiovascular health.
- Accurate assessment of these structures is vital for diagnosing and managing cardiovascular diseases.
Purpose of the Study:
- To elucidate the utility of three-dimensional echocardiography (3DE) in assessing the aortic valve.
- To demonstrate the application of 3DE in evaluating the aorta.
Main Methods:
- Review of clinical applications and imaging techniques of 3DE.
- Analysis of illustrative cases showcasing 3DE's capabilities.
Main Results:
- 3DE offers comprehensive visualization of aortic valve morphology and function.
- 3DE provides detailed anatomical and pathological insights into the aorta.
Conclusions:
- Three-dimensional echocardiography is a valuable tool for the detailed assessment of the aortic valve and aorta.
- The manuscript highlights the practical application of 3DE with illustrative figures and video clips.
Abstract:
We describe the role of three-dimensional echocardiography in the assessment of the aortic valve and the aorta. The manuscript is heavily illustrated with figures and movie clips.
Related Concept Videos
Aortic Regurgitation II: Clinical Features and Diagnostic Tests
Assessment of the Cardiovascular System IV: Auscultation
Normal Heart Sounds
S1 (First Heart Sound)-
S1 is made by the closure of the mitral and tricuspid valves (atrioventricular valves), marking the beginning of systole.
S2 (Second Heart Sound)-
S2 is made by the closure of the aortic and pulmonic valves (semilunar valves), marking the end of the systole.
Aortic Regurgitation I: Introduction

