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Published on: June 16, 2020
MR imaging features of Lhermitte-Duclos disease: Case reports and literature review
Han-Wen Zhang1, Yuan-Qing Zhang2, Xiao-Lei Liu1
1Department of Radiology, The First Affiliated Hospital of Shenzhen University, Health Science Center, Shenzhen Second People's Hospital, 3002 SunGangXi Road, Shenzhen, China.
Rationale:
Lhermitte-Duclos disease (LDD) is a rare tumor of the nervous system with a typical "tiger striped'" sign, but its features on functional magnetic resonance imaging (fMRI) are still inconclusive.
Patient Concerns:
To explore the characteristics of LDDs using fMRI.
Diagnoses:
We report 3 cases of pathologically confirmed LDDs.
Interventions:
Three patients underwent brain tumor surgery.
Outcomes:
All the patients had a good prognosis.
Lessons:
Magnetic resonance spectroscopy and susceptibility-weighted imaging combined with conventional MRI can be used to better diagnose LDDs. Perfusion-weighted imaging is not specific for distinguishing cerebellar tumors. The combined application of fMRI and conventional MRI can improve the accuracy of LDD diagnoses.

