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A rhodamine derivative probe for highly selective detection of Cu(II)
Liming Hu1, Yifan Lin1, Peng Wang1
1College of Life Science and Chemistry, Beijing Key Laboratory of Environmental and Oncology, Faculty of Environment and Life, Beijing University of Technology, 100124 Beijing, China.
Background:
Abnormal Cu(II) ions levels may affect many biological functions, and it is of great importance to detect Cu(II) ions in organisms.
Methods:
Herein, we report a near-infrared (NIR) fluorescent probe EtRh-N-NH2 for the detection of Cu(II). In the probe structure, a rhodamine core was used, and a hydrazine group was employed as the responsive site. Results & Conlusions: EtRh-N-NH2 displayed sensitive, specific and fast response upon Cu(II) with excellent linear relationship between the concentration and fluorescence emission intensity in 0-1 μM range. The releasing EtRh-COOH exhibited 762 nm of emission wavelength with a 75 nm of Stokes shift.
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