Related Experiment Video

Updated: Oct 5, 2025

Reduction in Left Ventricular Wall Stress and Improvement in Function in Failing Hearts using Algisyl-LVR
07:24

Reduction in Left Ventricular Wall Stress and Improvement in Function in Failing Hearts using Algisyl-LVR

Published on: April 8, 2013

24.4K

Coronary revascularization in patients with left ventricle systolic dysfunction, current challenges and clinical

Ahmed Abdalwahab1,2, Ayman Al-Atta1, Mohaned Egred1

  • 1Department of Cardiology, Freeman Hospital, NE7 7DN Newcastle upon Tyne, UK.

Reviews in Cardiovascular Medicine
|January 29, 2022
PubMed

Insights

Coronary revascularization outcomes in patients with left ventricle systolic dysfunction (LVSD) require further study. This review examines the role of ischemia and viability assessment in guiding revascularization decisions for LVSD patients.

Area of Science:

  • Cardiology
  • Cardiac Surgery
  • Interventional Cardiology

Background:

  • Outcomes of coronary revascularization in patients with left ventricle systolic dysfunction (LVSD) are not well-established.
  • Decision-making regarding revascularization timing and strategy in LVSD is complex, involving procedural risks and assessment limitations.

Purpose of the Study:

  • To review the role of LVSD in patients undergoing coronary revascularization.
  • To examine the significance of ischemia and viability assessment in this patient population.
  • To synthesize literature on the outcomes of surgical and percutaneous coronary revascularization in LVSD patients.

Main Methods:

  • Literature review of studies on coronary revascularization in patients with LVSD.
  • Analysis of the role of ischemia and viability assessment as prognostic and therapeutic targets.
  • Synthesis of outcomes data from both surgical and percutaneous revascularization procedures.

Main Results:

  • The role of viability assessment as a prognostic marker and therapeutic target in LVSD remains debated.
  • Revascularization decisions are challenged by difficulties in assessing ischemia, viability, and predicting LV recovery.
  • Existing literature on outcomes of revascularization in LVSD is limited.

Conclusions:

  • Further research is needed to clarify the benefits and optimal timing of coronary revascularization in patients with LVSD.
  • Improved methods for assessing ischemia and viability are crucial for guiding treatment decisions.
  • The prognostic value of left ventricular function recovery post-revascularization warrants further investigation.

Keywords:
Coronary artery bypass graftIschemiaLeft ventricle systolic dysfunctionPercutaneous coronary interventionViability

More Related Videos

Author Spotlight: Enhancing Coronary Artery Revascularization05:25

Author Spotlight: Enhancing Coronary Artery Revascularization

Published on: September 15, 2023

887
Evaluation of Coronary Flow Reserve After Myocardial Ischemia Reperfusion in Rats06:32

Evaluation of Coronary Flow Reserve After Myocardial Ischemia Reperfusion in Rats

Published on: June 28, 2019

8.1K

Related Concept Videos

Coronary Artery Disease III: Clinical Manifestations01:30

Coronary Artery Disease III: Clinical Manifestations

Coronary Artery Disease (CAD) is a primary health risk worldwide, leading to significant morbidity and mortality. The condition arises from the buildup of atherosclerotic plaques within the coronary arteries, resulting in diminished blood supply to the heart muscle.The clinical manifestations of CAD vary widely, from asymptomatic stages to severe, life-threatening conditions. Understanding these manifestations is crucial for early diagnosis and effective management.Angina Pectoris: The Warning...
57
Heart Failure III: Clinical Manifestations01:26

Heart Failure III: Clinical Manifestations

Heart failure (HF) manifests primarily as dyspnea, fatigue, and fluid retention, resulting in peripheral and pulmonary edema. Symptoms may vary depending on which ventricle is more affected, left or right.Left-Sided Heart FailureAlso known as left ventricular failure, this condition results from the left ventricle's inability to fill or eject sufficient blood into the systemic circulation. It leads to pulmonary congestion, which occurs when the left ventricle fails to eject blood effectively...
75
Acute Coronary Syndrome II: Pathophysiology and Clinical Manifestations01:19

Acute Coronary Syndrome II: Pathophysiology and Clinical Manifestations

The pathophysiology of Acute Coronary Syndrome [ACD] involves several key processes:The main underlying cause of ACD is atherosclerosis, a chronic inflammatory disease characterized by the buildup of lipid-laden plaques within the coronary arteries.As the atherosclerotic plaque grows in the coronary artery, it may become unstable due to the formation of a lipid-rich core and a thin fibrous cap. Inflammatory cells within the plaque, such as macrophages, secrete enzymes that degrade the...
70
Cardiomyopathy V: Interprofessional Care01:29

Cardiomyopathy V: Interprofessional Care

Managing cardiomyopathy involves addressing underlying or precipitating causes, treating heart failure with medications, and implementing dietary changes and a balanced exercise and rest regimen.Lifestyle ModificationsCardiomyopathy patients should adopt a low-sodium diet to reduce fluid retention and manage heart failure. A personalized exercise and rest plan helps maintain physical fitness without overstraining the heart. Avoiding alcohol and tobacco is essential to prevent further damage to...
57
Heart Failure II: Pathophysiology01:29

Heart Failure II: Pathophysiology

Systolic Heart Failure and Compensatory MechanismsSystolic heart failure (also termed HFrEF, Heart Failure with Reduced Ejection Fraction) is the most prevalent type of heart filure. It results in a decreased volume of blood being pumped from the ventricle. The aortic arch and carotid sinuses have baroreceptors that detect reduced blood pressure, triggering the sympathetic nervous system (SNS) to release epinephrine and norepinephrine. Initially, this response aims to boost heart rate and...
92
Aortic Regurgitation III: Medical Management01:25

Aortic Regurgitation III: Medical Management

Aortic regurgitation (AR) is when the aortic valve does not close or seal properly, leading to backward blood circulation from the aorta into the left ventricle during diastole. Common causes of AR include rheumatic heart disease, congenital valve defects, and aortic root dilation. Managing AR requires a multifaceted approach to alleviate symptoms, preserve left ventricular function, and address the underlying cause of the regurgitation. Patients with symptomatic AR or significant left...
63