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Innovative approach for first-trimester fetal organ volume measurements using a Virtual Reality system: The

Clarissa J Wiertsema1,2, Chalana M Sol1,2, Annemarie G M G J Mulders3

  • 1The Generation R Study Group, Erasmus University Medical Center, Rotterdam, The Netherlands.

The Journal of Obstetrics and Gynaecology Research
|January 29, 2022
PubMed
Summary
This summary is machine-generated.

This study found that while fetal organ volume measurements using 3D ultrasound and Virtual Reality showed good intraobserver reproducibility, interobserver results were suboptimal. Further improvements may come from advanced post-processing algorithms for research applications.

Keywords:
3D ultrasoundfetusfirst trimesterorgan developmentreproducibilityvirtual reality

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Area of Science:

  • Medical Imaging
  • Fetal Medicine
  • Virtual Reality Applications

Background:

  • First-trimester fetal organ volume assessment is crucial for monitoring development.
  • Three-dimensional (3D) ultrasound and Virtual Reality (VR) offer innovative approaches for fetal measurements.

Purpose of the Study:

  • To evaluate the reproducibility of first-trimester fetal heart, lung, and kidney volume measurements.
  • To assess the reliability of 3D ultrasound and VR system in fetal organ volumetry.

Main Methods:

  • Prospective cohort study involving 25 fetuses in the first trimester.
  • 3D ultrasound datasets were acquired by three sonographers.
  • Virtual Reality (V-scope application) was used for fetal organ volume assessments by two independent researchers.

Main Results:

  • High intraobserver reproducibility was observed for fetal heart, lung, and kidney volumes (ICC ≥0.86).
  • Sufficient interobserver agreement was found only for right lung volume measurements.
  • Significant measurement differences between observers were noted for left lung, heart, and kidney volumes (p<0.05).

Conclusions:

  • The Virtual Reality approach demonstrated sufficient intraobserver reproducibility but suboptimal interobserver reproducibility for first-trimester fetal organ volumetry.
  • Current application shows promise for research settings, with potential for improvement via novel post-processing algorithms.