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25-hydroxyvitamin D in older adults: Which factors really matter?
Lucas Baptistella Barbieri1, Marco Aurélio Costa da Silva2, Fabiana de Souza Orlandi2
1Departament of Medicine, Federal University of São Carlos, Rod. Washington Luís, km 235, Postal code: 13565-905 São Carlos, SP, Brazil.
Background And Objectives:
This study investigated the interaction between a set of factors commonly associated with vitamin D production and nutritional intake and serum 25(OH)D levels among older adults.
Methods:
Cross-sectional study on 346 adults over 60 years. Serum 25(OH)D levels were measured following routine biochemical laboratory protocols. Multivariable logistic regression investigated which factors were independently associated with vitamin D deficiency.
Results:
The prevalence of vitamin D deficiency and insufficiency was 35.3% and 44.2%, respectively. The multivariable logistic regression showed gender and BMI as independent adjustment measures for serum 25(OH)D levels; all other associations were non-significant.
Conclusions:
Sex and BMI prevail as principal determinants of serum 25(OH)D levels among older adults. BMI seems to have a more pronounced influence on serum 25(OH)D levels of females compared to males. Healthcare professionals should consider active screening for changes in serum 25(OH)D levels in older obese adults, especially females.
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