Related Experiment Video
Updated: Jul 15, 2026

Setting Up a Stroke Team Algorithm and Conducting Simulation-based Training in the Emergency Department - A Practical Guide
Published on: January 15, 2017
Effects of delay to stroke unit admission in patients with ischemic and hemorrhagic stroke
Bing Yu Chen1, Himanshu Gupta1, Clifford Yacas2
1Division of Neurology, Department of Medicine, McMaster University, Hamilton, Ontario, Canada.
Insights
Delays in transferring acute stroke patients to a central stroke unit are linked to longer hospital stays and worse functional outcomes. Optimizing transfer protocols is crucial for improving stroke patient care and recovery.
Area of Science:
- Neurology
- Public Health
- Healthcare Management
Background:
- Timely transfer to specialized stroke units is critical for optimal acute stroke patient management.
- Peripheral institutions often transfer patients to comprehensive stroke centers (CSCs) for advanced care.
Purpose of the Study:
- To investigate the association between delayed transfer to a central stroke unit and patient outcomes.
- To identify factors contributing to transfer delays in acute stroke care.
Main Methods:
- Retrospective cohort study of 1435 acute stroke patients admitted to a CSC from three emergency departments (EDs) between 2016-2018.
- Primary outcomes included length of stay, functional status at 3 months, discharge destination, and time to stroke investigations.
- Analysis examined the impact of transfer delays on these outcomes and identified contributing factors.
Main Results:
- Each day of transfer delay correlated with a 2.0-day increase in length of stay and an 11.5-hour delay in vascular imaging.
- Delays were associated with reduced odds of nondisabled functional status at 3 months (OR 0.98).
- Factors influencing delay included stroke onset timing, brain imaging, admission service, and transfer from a primary stroke center (PSC).
Conclusions:
- Transfer delays from PSCs to a CSC negatively impact hospital stay duration and functional outcomes for acute stroke patients.
- Streamlining inter-facility transfer processes is essential for improving stroke care delivery and patient prognosis.
Objective:
To determine the association between delay in transfer to a central stroke unit from peripheral institutions and outcomes.
Methods:
We conducted a retrospective cohort study of all patients with acute stroke, admitted to a comprehensive stroke center (CSC) from three emergency departments (EDs), between 2016 and 2018. The primary outcomes were length of stay, functional status at 3 months, discharge destination, and time to stroke investigations.
Results:
One thousand four hundred thirty-five patients were included, with a mean age of 72.9 years, and 92.4% ischemic stroke; 663 (46.2%) patients were female. Each additional day of delay was associated with 2.0 days of increase in length of stay (95% confidence interval [CI] 0.8-3.2, p = 0.001), 11.5 h of delay to vascular imaging (95% CI 9.6-13.4, p < 0.0001), 24.2 h of delay to Holter monitoring (95% CI 7.9-40.6, p = 0.004), and reduced odds of nondisabled functional status at 3 months (odds ratio 0.98, 95% CI 0.96-1.00, p = 0.01). Factors affecting delay included stroke onset within 6 h of ED arrival (605.9 min decrease in delay, 95% CI 407.9-803.9, p < 0.0001), delay to brain imaging (59.4 min increase in delay for each additional hour, 95% CI 48.0-71.4, p < 0.0001), admission from an alternative service (3918.7 min increase in delay, 95% CI 3621.2-4079.9, p < 0.0001), and transfer from a primary stroke center (PSC; 740.2 min increase in delay, 95% CI 456.2-1019.9, p < 0.0001).
Conclusion:
Delay to stroke unit admission in a system involving transfer from PSCs to a CSC was associated with longer hospital stay and poorer functional outcomes.
Related Concept Videos
Stroke: Introduction and Types
Ischemic Stroke l: Introduction
Ischemic Stroke ll: Pathophysiology
Hemorrhagic Stroke l: Introduction
Hemorrhagic Stroke ll: Pathophysiology

