Microfluidics based point-of-care for disease diagnostics
Gargi Bhattacharjee1, Rupesh Maurya1, Khalid J Alzahrani2
1Department of Biosciences, School of Science, Indrashil University, Rajpur, Mehsana, Gujarat, India.
Progress in Molecular Biology and Translational Science
|January 31, 2022
Summary
Microfluidics technology offers low-cost, rapid, and sensitive disease diagnosis by integrating lab-on-chip systems. This approach enhances early detection of diseases and pathogens through advanced biomarker analysis.
Area of Science:
- Biotechnology
- Medical Diagnostics
- Microfluidics
Background:
- Microfluidics platforms are essential in biological and biotechnological applications.
- They minimize reagent consumption by reducing reaction volumes.
- Applications include early disease diagnosis, pathogen detection, and high-throughput screening.
Purpose of the Study:
- To highlight recent advancements in microfluidics for disease diagnosis.
- To showcase the integration of microfluidics and lab-on-chip for comprehensive biomarker analysis.
Main Methods:
- Integration of microfluidics with lab-on-chip technology.
- Development of paper-based lateral flow detection modes.
Main Results:
- Microfluidics enables low-cost, rapid, sensitive, and user-friendly disease detection.
- The technology facilitates sample preparation, extraction, analysis, and biomarker detection.
Conclusions:
- Microfluidics platforms are pivotal for scalable and efficient disease diagnosis.
- Recent developments focus on integrated systems for comprehensive biomarker analysis and early disease detection.
