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Intestinal Infarction in COVID-19 Pandemic: A Case Series

Maryam Sarkardeh1,2, Amin Dalili1,2, Naser Tayyebi Meibodi3

  • 1Surgical Oncology Research Center, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.

Iranian Journal of Pathology
|January 31, 2022
PubMed

Insights

Severe COVID-19 pneumonia may lead to intestinal necrosis and mesenteric ischemia. This study highlights a potential link between coronavirus infection and gastrointestinal vascular events, urging physician awareness.

Area of Science:

  • Gastroenterology
  • Infectious Diseases
  • Vascular Surgery

Background:

  • The global spread of novel coronavirus disease 2019 (COVID-19) presents numerous health risks.
  • While respiratory symptoms are common, COVID-19 may also induce coagulation disorders and thrombolytic events.
  • Potential complications include disrupted visceral blood flow and mesenteric ischemia.

Purpose of the Study:

  • To report cases of acute mesenteric ischemia in patients with COVID-19.
  • To describe pathological findings associated with COVID-19 and mesenteric ischemia.
  • To investigate the relationship between severe COVID-19 and mesenteric vascular events.

Main Methods:

  • Case series of four patients with severe COVID-19 pneumonia and intestinal necrosis.
  • Collection of clinical data, imaging, and microscopic findings.
  • Review of operative findings in affected patients.

Main Results:

  • Four hospitalized patients with severe COVID-19 also presented with intestinal necrosis.
  • Pathological findings suggest a link between the infection and vascular complications.
  • The cases indicate a correlation between coronavirus infection and mesenteric vascular events.

Conclusions:

  • Severe COVID-19 pneumonia can be associated with intestinal necrosis and mesenteric ischemia.
  • Physicians must be vigilant for gastrointestinal thrombosis symptoms in COVID-19 patients.
  • This study underscores the potential for COVID-19 to precipitate serious mesenteric vascular complications.

Keywords:
Abdominal CT ScanCOVID-19Mesenteric IschemiaThrombosis

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