Organ Care System Heart™ in donors requiring high-risk excision of suspected neoplastic lesions

Area of Science:

• Cardiology
• Transplant Surgery
• Organ Preservation

Background:

• Heart transplantation is the optimal treatment for end-stage heart failure.
• A significant limitation is the scarcity of suitable donor organs.
• Donor organ preservation is critical to minimize ischemia-reperfusion injury.

Purpose of the Study:

• To evaluate the utility of Organ Care Systems in managing donor organs requiring complex excisions.
• To assess the potential of Organ Care Systems as a time buffer in challenging donor scenarios.
• To demonstrate the feasibility of using Organ Care Systems for high-risk donor organ retrieval.

Main Methods:

• Three cases involving suspected lesions in potential heart donors were analyzed.
• Organs were retrieved and placed into Organ Care Systems prior to excision of lesions.
• Organ preservation and assessment were performed using the device.

Main Results:

• Organ Care Systems successfully preserved donor hearts during complex excision procedures.
• The device provided a necessary time buffer, allowing for thorough assessment and management of suspected lesions.
• This approach facilitated the utilization of organs that might otherwise have been discarded.

Conclusions:

• Organ Care Systems can be effectively utilized as a time buffer in specific heart donor scenarios.
• This technology enhances the potential to expand the donor pool by managing complex organ retrievals.
• The use of Organ Care Systems in these peculiar situations is feasible and beneficial for heart transplantation.