Related Experiment Video
Updated: Oct 5, 2025

Minimally Invasive Isolated Limb Perfusion (MI-ILP) for Locally Advanced Melanomas and Sarcomas of the Extremity
Published on: January 31, 2025
Surgical Intervention for Phlegmasia Cerulea Dolens in a 61-Year-Old Cancer Patient
Christopher Ruben-Castillo1, Cesar Cuen-Ojeda1, Gabriel Lopez-Peña1
1Section of Vascular Surgery and Endovascular Therapy, Department of Surgery, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico.
Insights
Phlegmasia cerulea dolens, a severe deep vein thrombosis complication, can be limb-threatening. Prompt open surgical thrombectomy successfully treated a patient, restoring venous flow and saving her leg.
Area of Science:
- Vascular Surgery
- Cardiovascular Medicine
Background:
- Phlegmasia cerulea dolens is a rare, severe complication of deep vein thrombosis (DVT).
- It presents with significant edema, pain, and cyanosis, potentially leading to limb ischemia and death.
Observation:
- A 61-year-old woman with breast cancer developed phlegmasia cerulea dolens in her left leg.
- The patient exhibited classic signs and symptoms of this critical condition.
Findings:
- Prompt treatment with open surgical thrombectomy and distal compression using an Esmarch bandage was performed.
- This intervention successfully restored venous flow and prevented limb loss.
Implications:
- Open surgical thrombectomy is a viable and effective treatment for limb-threatening phlegmasia cerulea dolens.
- Early surgical intervention can be life- and limb-saving in acute DVT complications.
Abstract:
Phlegmasia cerulea dolens, a rare and potentially fatal complication of acute deep vein thrombosis, is characterized by substantial edema, intense pain, and cyanosis. Phlegmasia cerulea dolens may compromise limb perfusion and lead to acute ischemia, gangrene, amputation, and death. We present the case of a 61-year-old woman with a history of breast cancer who had signs and symptoms of phlegmasia cerulea dolens in her left leg. She was treated promptly with open surgical thrombectomy and sequential distal compression with use of an Esmarch bandage to ensure complete thrombus extraction. These techniques restored venous flow and saved her leg. Open surgical thrombectomy should be considered in the presence of limb-threatening acute deep vein thrombosis presenting as phlegmasia cerulea dolens.
More Related Videos
Related Concept Videos
Peripheral Artery Disease III: Interprofessional Care
Varicose Veins II: Diagnostic Studies and Interprofessional Care
Peripheral Artery Disease V: Postoperative Nursing Management
Flail Chest-II
Assessment:
1. Clinical Evaluation:
History:
Peripheral Artery Disease IV: Nursing Management
Venous Thrombosis III: Interprofessional Care

