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Updated: Oct 5, 2025

A High Resolution Method to Monitor Phosphorylation-dependent Activation of IRF3
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A High Resolution Method to Monitor Phosphorylation-dependent Activation of IRF3

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OTUD7B deubiquitinates SQSTM1/p62 and promotes IRF3 degradation to regulate antiviral immunity

Weihong Xie1,2, Shuo Tian1, Jiahui Yang2

  • 1MOE Key Laboratory of Gene Function and Regulation, State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-sen University, Guangzhou, P. R. China.

Autophagy
|January 31, 2022
PubMed

Keywords:
Antiviral immunitycargo receptordeubiquitinationselective autophagytype I interferon signaling

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