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Usability, acceptability, and feasibility of a High-Density Microarray Patch (HD-MAP) applicator as a delivery method
Cristyn Davies1,2, Melody Taba1,2, Lucy Deng1,3
1Specialty of Child and Adolescent Health, The Children's Hospital at Westmead Clinical School, Faculty of Medicine and Health, The University of Sydney, Westmead, Australia.
Human Vaccines & Immunotherapeutics
|January 31, 2022
Summary
High-density microarray patch (HD-MAP) vaccines are usable and acceptable for vaccine delivery by healthcare workers and for self-administration. Training can further improve HD-MAP usability and acceptance.
Area of Science:
- Vaccinology
- Microneedle Technology
- Public Health
Background:
- High-density microarray patch (HD-MAP) vaccines present a novel approach to enhance vaccine acceptance and utilization.
- Assessing the usability and acceptability of HD-MAP technology among healthcare professionals is crucial for its successful implementation.
Purpose of the Study:
- To evaluate the usability and acceptability of the HD-MAP applicator among professional immunizers (PIs) and healthcare workers (HCWs) in Australia.
- To determine the feasibility of HD-MAP administration by healthcare professionals and for self-administration.
Main Methods:
- A feasibility study involving PIs and HCWs administering and receiving simulated HD-MAP doses.
- Usability assessment against predefined criteria, complemented by participant surveys and qualitative interviews/focus groups.
- Quantitative analysis of survey data using descriptive statistics and thematic analysis of interview transcripts.
Main Results:
- High usability and acceptability were reported for HD-MAP use by healthcare professionals and for self-administration with safety measures.
- Most administrations met essential criteria, though PIs slightly under-applied the device compared to HCWs.
- PIs expressed safety concerns regarding home administration but found layperson self-administration acceptable in specific contexts (emergency, pandemic, remote settings).
Conclusions:
- HD-MAP administration was found to be usable and acceptable by healthcare professionals and for self-administration.
- End-user education and comprehensive training are likely to enhance the overall usability and acceptance of HD-MAP technology.
