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Related Concept Videos

The Thyroid Gland01:23

The Thyroid Gland

4.6K
The thyroid gland is a small, butterfly-shaped gland located in the neck and covers the anterior surface of the trachea. The gland has two lateral lobes connected by a thin tissue mass called the isthmus. Internally, each lobe comprises many small spherical structures known as thyroid follicles, surrounded by a network of blood vessels.
The follicles have a central cavity lined by simple cuboidal to squamous epithelial cells called follicular cells. These cells produce the glycoprotein...
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Related Experiment Video

Updated: Oct 5, 2025

Transoral Endoscopic Thyroidectomy Vestibular Approach for Thyroid Lobectomy
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Thyroid lobectomy for low-risk thyroid cancers.

B Puttergill1, S Khan1, I Christakis2

  • 1Oxford University Hospital NHS Trust, UK.

Annals of the Royal College of Surgeons of England
|February 1, 2022
PubMed
Summary
This summary is machine-generated.

Thyroid lobectomy for low-risk differentiated thyroid cancer (DTC) is recommended but not widely adopted. This study reviewed practice in two units, finding lobectomy-only is common, but a standardized approach and follow-up protocols are needed.

Keywords:
RiskThyroid cancerThyroid glandThyroid neoplasmsThyroidectomy

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Area of Science:

  • Endocrinology
  • Surgical Oncology
  • Thyroid Cancer Research

Background:

  • The 2016 American Thyroid Association (ATA) guidelines suggest thyroid lobectomy for low-risk differentiated thyroid cancer (DTC).
  • Widespread adoption of this less invasive approach has been slow.
  • This study examines the implementation of these guidelines in regional surgical practices.

Purpose of the Study:

  • To assess the adoption rate of thyroid lobectomy for low-risk DTC.
  • To identify patient characteristics and surgical outcomes following lobectomy-only.
  • To evaluate the need for standardized follow-up protocols for patients treated with lobectomy-only.

Main Methods:

  • Retrospective review of 288 patients undergoing thyroid surgery between January 2016 and December 2018.
  • Analysis of preoperative cytology, nodule size, and postoperative outcomes.
  • Identification of patients who underwent completion thyroidectomy based on ATA recommendations.

Main Results:

  • Differentiated thyroid cancer (DTC) was diagnosed in 33% of patients (95/288).
  • 39% of patients required completion thyroidectomy due to tumor size or adverse histological features.
  • Tumor size was the only significant factor associated with the likelihood of completion thyroidectomy (p < 0.05).
  • Ten patients with T1a/b DTC and no high-risk features were discharged without further follow-up.

Conclusions:

  • Lobectomy-only is the surgical practice for two-thirds of patients with DTC in the studied regional units.
  • A more standardized approach and clear protocols for long-term follow-up are necessary for patients undergoing lobectomy-only for low-risk DTC.