Related Experiment Video

Updated: Aug 10, 2026

A Large Animal Model for Acute Kidney Injury by Temporary Bilateral Renal Artery Occlusion
09:02

A Large Animal Model for Acute Kidney Injury by Temporary Bilateral Renal Artery Occlusion

Published on: February 2, 2021

4.6K

Coronavirus Disease 2019 Infection Presenting with Renal Infarction: A Rare Case Report

Suman Sethi1, Sudhir Mehta1, Rajesh Mahajan2

  • 1Department of Nephrology, Dayanand Medical College and Hospital, Ludhiana, Punjab, India.

Saudi Journal of Kidney Diseases and Transplantation : an Official Publication of the Saudi Center for Organ Transplantation, Saudi Arabia
|February 1, 2022
PubMed

Insights

This case report highlights a rare instance of renal infarction, a serious kidney complication, in a patient with coronavirus disease 2019 (COVID-19). The findings emphasize the diverse and severe vascular complications associated with this viral infection.

Area of Science:

  • Nephrology
  • Infectious Diseases
  • Vascular Medicine

Background:

  • Coronavirus disease 2019 (COVID-19) is a global pandemic with significant systemic effects.
  • Kidney involvement, including acute kidney injury, is common in COVID-19 patients, particularly the critically ill.
  • While hypercoagulable states and thromboembolic events are known complications, renal infarction is an infrequent manifestation.

Observation:

  • A patient presented with COVID-19 pneumonia and acute kidney injury.
  • During further evaluation for gastrointestinal symptoms, computed tomography angiography revealed renal infarction.
  • This case underscores a rare vascular complication of COVID-19 infection.

Findings:

  • COVID-19 infection can lead to rare but severe vascular complications such as renal infarction.
  • The mechanisms may involve direct viral effects, cytokine storm, or hemodynamic changes contributing to thrombosis.
  • Early detection of renal infarction is crucial in patients with COVID-19 presenting with kidney injury.

Implications:

  • Clinicians should consider renal infarction in the differential diagnosis of kidney injury in COVID-19 patients.
  • This case expands the understanding of COVID-19's potential to cause diverse thromboembolic events.
  • Further research is needed to elucidate the precise mechanisms and optimal management strategies for COVID-19-associated renal infarction.

More Related Videos

Bilateral Renal Ischemia-Reperfusion Model for Acute Kidney Injury in Mice02:45

Bilateral Renal Ischemia-Reperfusion Model for Acute Kidney Injury in Mice

Published on: February 2, 2024

1.9K
Unilateral Ureteral Obstruction Model for Investigating Kidney Interstitial Fibrosis04:37

Unilateral Ureteral Obstruction Model for Investigating Kidney Interstitial Fibrosis

Published on: April 25, 2025

839

Related Concept Videos

Acute Pyelonephritis I: Introduction01:27

Acute Pyelonephritis I: Introduction

Pyelonephritis is a bacterial infection that primarily affects the renal parenchyma and collecting system, including the renal pelvis, tubules, and interstitial tissue of one or both kidneys. It can be classified as either acute—a sudden, severe infection—or chronic, which refers to long-term or recurrent kidney infections.The primary cause of acute pyelonephritis (APN) is bacterial infection, with Escherichia coli accounting for approximately 70-80% of cases. Other bacteria, such as Proteus,...
Acute Kidney Injury I: Introduction01:22

Acute Kidney Injury I: Introduction

Introduction:Acute Kidney Injury (AKI) describes a swift decrease in kidney function occurring over hours to days, characterized by the kidneys' failure to remove waste products from the bloodstream. This leads to dangerous complications like metabolic acidosis, fluid overload, and electrolyte imbalances, such as hyperkalemia, which can cause life-threatening arrhythmias. AKI is common in both hospital and outpatient settings, often triggered by dehydration, sepsis, or exposure to nephrotoxic...
Acute Kidney Injury II: Pathophysiology01:29

Acute Kidney Injury II: Pathophysiology

Acute kidney injury (AKI) causes are categorized into three primary categories based on the location of the injury: prerenal, intrarenal (or intrinsic), and postrenal causes. This classification guides clinical management and illustrates how different pathways can impair kidney function.Etiology and Pathophysiology of Acute Kidney Injury1. Prerenal causesEtiology: Prerenal Acute Kidney Injury, the most common type, occurs when reduced blood flow to the kidneys decreases filtration capacity...
Acute Kidney Injury III: Clinical Manifestations01:29

Acute Kidney Injury III: Clinical Manifestations

Acute Kidney Injury (AKI) progresses through distinct clinical phases: the oliguric, diuretic, and recovery phases, each marked by unique manifestations and challenges.Oliguric Phase:The oliguric phase is the initial stage of AKI, typically lasting 10 to 14 days. This phase is marked by a significant reduction in urine output, usually less than 400 mL per day, indicating decreased kidney function. Fluid retention is a prominent feature, leading to symptoms such as edema, hypertension, and...
Acute Kidney Injury IV: Diagnostic Studies and Prevention01:30

Acute Kidney Injury IV: Diagnostic Studies and Prevention

Accurate diagnosis and effective prevention are critical in managing Acute Kidney Injury (AKI), which is linked to high mortality rates ranging from 10% to 80%. Timely recognition of at-risk patients and careful monitoring can significantly reduce the likelihood of kidney damage.Diagnostic Assessments:The diagnostic process starts with a comprehensive medical history to identify prerenal, intrarenal, and postrenal causes.Prerenal causes, such as dehydration, hypotension, or blood loss, should...
Chronic Kidney Disease II: Clinical Manifestations01:24

Chronic Kidney Disease II: Clinical Manifestations

Chronic Kidney Disease (CKD) progressively impairs multiple body systems due to the accumulation of uremic toxins, which disrupt cellular functions across various organs.Neurologic symptomsNeurologic symptoms often arise early in CKD, as uremic toxin buildup drives changes in cognitive and motor functions. Patients frequently experience fatigue, headache, confusion, difficulty concentrating, and, in severe cases, seizures. Peripheral neuropathy commonly manifests as burning sensations in the...