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Published on: February 2, 2015
Fetal Ventriculomegaly and Hydrocephalus - What Shouldn't be Missed on Imaging?
Liat Ben Sira1, Danil A Kozyrev2, Dafna Ben Bashat3
1Division of Pediatric Radiology, Tel Aviv Sourasky Medical Center; Sackler Faculty of Medicine; Sagol School of Neuroscience, Tel Aviv University, Tel Aviv, Israel.
Insights
Fetal ventriculomegaly, a common prenatal diagnosis, requires identifying subtle abnormalities for accurate prognoses. This review explores fetal MRI patterns to predict clinical course and treatment effectiveness for fetal hydrocephalus.
Area of Science:
- Radiology
- Prenatal Diagnosis
- Neuroimaging
Background:
- Fetal ventriculomegaly is a frequent prenatal diagnosis.
- Subtle anomalies accompanying ventriculomegaly aid in prognosis, ranging from normal outcomes to neurodevelopmental issues.
- Accurate prognostication is crucial for managing potential long-term effects.
Purpose of the Study:
- To review the pathogenesis and imaging patterns of fetal ventriculomegaly and hydrocephalus.
- To highlight the utility of a pattern-recognition approach using fetal Magnetic Resonance Imaging (MRI).
- To explore how radiological findings can inform clinical course prediction and therapeutic efficacy.
Main Methods:
- Review of existing literature on fetal ventriculomegaly and hydrocephalus.
- Focus on pattern recognition using fetal MRI data.
- Analysis of imaging findings correlated with clinical outcomes.
Main Results:
- Fetal MRI provides detailed insights into the pathogenesis of ventriculomegaly and hydrocephalus.
- Pattern recognition on MRI aids in differentiating causes and predicting severity.
- Identification of subtle associated anomalies is key for accurate prognostication.
Conclusions:
- Fetal MRI is a valuable tool for diagnosing and characterizing fetal ventriculomegaly and hydrocephalus.
- A pattern-recognition approach using fetal MRI can improve prognostication.
- This radiological approach may enhance the prediction of clinical course and guide therapeutic strategies for fetal hydrocephalus.
Abstract:
Fetal ventriculomegaly is one of the most frequently diagnosed abnormalities detected prenatally. The finding of additional subtle abnormalities can facilitate accurate prognoses, which may range from normal outcomes to significant neurodevelopmental sequelae. Pathogenesis and imaging patterns of ventriculomegaly and hydrocephalus in the fetus based on the pattern-recognition approach using fetal MRI are reviewed in this paper. This radiological approach may shed light on clinical course prediction and therapeutic efficacy of hydrocephalus in the fetus.
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