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Synchronous Bilateral Primary Testicular Tumors With Discordant Histopathology.
Louisa Liu1, Crystal Wang2, Sameer Shah3
1Internal Medicine, University of California, Riverside School of Medicine, Riverside, USA.
Cureus
|February 1, 2022
Summary
Bilateral testicular tumors with different histologies are rare. Management of these synchronous germ cell tumors should prioritize the most aggressive component for optimal patient outcomes.
Area of Science:
- Oncology
- Urology
Background:
- Synchronous bilateral testicular tumors with distinct histologies are exceptionally rare clinical occurrences.
- Germ cell tumors (GCTs) are the most common testicular cancers in young men.
Observation:
- A 20-year-old male presented with a unilateral testicular mass, subsequently found to have bilateral testicular masses on ultrasound.
- Pathology revealed a mixed germ cell tumor (teratoma, seminoma, germ cell neoplasia in situ) on the left and pure seminomas on the right.
Findings:
- The patient underwent bilateral orchiectomy for synchronous, histologically distinct bilateral testicular tumors.
- Active surveillance was initiated post-operatively, with the patient remaining in remission at 18 months.
Implications:
- This case highlights the importance of individualized management strategies for bilateral testicular germ cell tumors.
- Treatment prioritization should be guided by the most aggressive histological component identified in either testis.
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