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Updated: Oct 5, 2025

Reduced Itraconazole Concentration and Durations Are Successful in Treating Batrachochytrium dendrobatidis Infection in Amphibians
Published on: March 14, 2014
Voriconazole-Induced Cholestatic Hepatotoxicity in an Immune Competent Patient
Yaser Mohammed1, Ahmed Abousamra1, Ahmed Atef I Abdeldayem2
1Internal Medicine, Conquest Hospital, East Sussex Healthcare NHS Trust, St Leonards-on-Sea, GBR.
Abstract:
Voriconazole is a frequently prescribed anti-fungal medication used in particular for invasive aspergillosis. Voriconazole-induced hepatotoxicity is a relatively rare but serious clinicopathologic entity. We report a patient presenting with impaired liver function test results pointing towards the cholestatic picture. The patient had initial blood tests to confirm cholestasis, followed by imaging modalities that did not show any obstruction along the common bile duct and/or pancreatic pathway. The patient's voriconazole dose reduction was advised, resulting in lower levels of abnormal liver function tests.
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