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Published on: January 11, 2019
Effect of hydrogen peroxide on erythrocyte temperature in vitro
Anton Kasatkin1, Aleksandr Urakov1
1Department of General and Clinical Pharmacology, Izhevsk State Medical Academy, Izhevsk, Kommunarov 281, 426034, Izhevsk, Russia.
Abstract:
Hydrogen peroxide (H2O2) is produced by most human cells. Cellular enzymes determine the features of the chemico-biological interaction between cells and hydrogen peroxide. The catalase is main intracellular enzyme that inactivates H2O2 in cells, in particular, erythrocytes. Catalase decomposes hydrogen peroxide into water and oxygen with the release of energy. However, until now, there is no convincing scientific data proving that the temperature of the cells changes when adding a solution of hydrogen peroxide. We conducted studies on how H2O2 solutions with different concentrations affect the change in erythrocytes temperature in vitro. Our results proved that toxic doses of hydrogen peroxide increase the temperature of red blood cells.
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