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Light-Controlled Fermentations for Microbial Chemical and Protein Production

Light-Controlled Fermentations for Microbial Chemical and Protein Production

Published on: March 22, 2022

Harnessing electrical-to-biochemical conversion for microbial synthesis.

Zhen Fang¹, Yinjie J Tang², Mattheos Ag Koffas³

¹Biofuels Institute, School of Environment and Safety Engineering, Jiangsu University, Zhenjiang 212013, China.

Current Opinion in Biotechnology

|February 1, 2022

Summary

This summary is machine-generated.

Electrical-to-biochemical conversion (E2BC) enables green biomanufacturing by driving cell metabolism. This review explores natural and artificial E2BC systems, synthetic biology, and compares E2BC with EC2BC for carbon-negative applications.

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Area of Science:

Biotechnology
Green Chemistry
Synthetic Biology

Background:

Electrical-to-biochemical conversion (E2BC) is crucial for driving cellular metabolism in biosynthesis.
E2BC presents a promising avenue for sustainable and green biomanufacturing processes.

Purpose of the Study:

To review natural E2BC processes and their mechanisms.
To discuss the development of artificial E2BC for microbial electrosynthesis.
To explore electrobiochemical system designs and compare E2BC with EC2BC for future applications.

Main Methods:

Review of natural E2BC mechanisms.
Analysis of artificial E2BC development for microbial electrosynthesis.
Examination of self-powered, light-assisted, and nano-biohybrid electrobiochemical systems.
Integration of synthetic biology approaches for enhanced microbial electrosynthesis.

Main Results:

Natural E2BC mechanisms provide a foundation for artificial systems.
Artificial E2BC allows for tunable microbial electrosynthesis.
Novel electrobiochemical system designs enhance efficiency and sustainability.
Synthetic biology tools are key for optimizing microbial electrosynthesis.

Conclusions:

E2BC is a versatile platform for green biomanufacturing.
Artificial E2BC and synthetic biology offer significant potential for industrial applications.
Comparison with EC2BC highlights pathways toward carbon-negative biomanufacturing.