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Association Between Negative Affectivity and Craving in Substance-Related Disorders: A Systematic Review and
Laura Cyr1, Laura Bernard1, Jean-Louis Pedinielli2
1LPCPP, Aix Marseille University, Aix-en-Provence, France; Clinique Saint-Barnabé, Ramsay Santé, Marseille, France.
Background:
A sizeable literature highlighted that negative affectivity and craving are both known to be implicated in relapses.
Objectives:
The present study synthetized the existing litterature to determine strength of the interaction between negative affectivity and craving for substance-related disorders including illicit drugs, alcohol and tobacco.
Methods:
We conducted a systematic review in accordance with PRISMA guidelines followed by a meta-analysis. Online computer databases PubMed, PsycINFO and Web of Science were searched systematically and thoroughly. Jamovi 1.8.1 Current version was used to conduct meta-analysis.
Results:
Thirty studies were included in the review, and 14 of these, including 2257 subjects, were used for meta-analysis. The raw correlation ranged from 0.17 to 0.58, which indicated weak to moderate association between negative affects and craving. In total, approximately 90% of the selection revealed a positive correlation between negative affects and craving. Alcohol and tobacco use disorders have received the most attention. Additionally, negative affectivity was often defined as a transient state rather than a stable personality trait.
Conclusions:
In both of our meta-analyses and in the narratively reported studies, we found that negative affectivity is an important component related to craving, but individual differences in craving reactivity existed.
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