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Updated: Oct 4, 2025

Three-Dimensional Imaging of the Vertebral Lymphatic Vasculature and Drainage using iDISCO+ and Light Sheet Fluorescence Microscopy
Published on: May 22, 2020
The "hyperdense basivertebral vein" sign: another marker of a CSF-venous fistula
Niklas Lützen1, Nico Kremers2, Christian Fung3
1Dept. of Neuroradiology, University Medical Center Freiburg, Faculty of Medicine, University of Freiburg, Breisacher Str. 64, 79106, Freiburg, Germany. niklas.luetzen@uniklinik-freiburg.de.
Abstract:
CSF-venous fistulas - initially described in 2014 - are a significant cause of spontaneous intracranial hypotension. Dynamic lateral decubitus digital subtraction and/or CT myelography typically show a hyperdense paraspinal vein. In case of a central drainage toward the internal vertebral venous plexus, it is the "hyperdense basivertebral vein" which should be searched for carefully.
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