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Acute infective endocarditis during COVID-19 pandemic time: The dark side of the moon
Roberto Lorusso1,2, Antonio M Calafiore3, Michele Di Mauro1
1Cardio-Thoracic Surgery Department, Heart and Vascular Centre, Maastricht University Medical Centre, Maastricht, The Netherlands.
Insights
The COVID-19 pandemic impacted acute cardiovascular syndromes, including acute infective endocarditis (AIE). Patients with AIE during the pandemic faced higher risks but had similar outcomes to pre-pandemic patients.
Area of Science:
- Cardiology
- Infectious Diseases
- Hospital Management
Background:
- The COVID-19 pandemic significantly altered hospital management and patient demographics for acute cardiovascular syndromes.
- Acute infective endocarditis (AIE) emerged as a frequent condition necessitating urgent surgical procedures during the pandemic.
- Previous research indicated higher-risk features in AIE patients during early pandemic waves.
Purpose of the Study:
- To comment on hospital management strategies for AIE patients during the COVID-19 pandemic.
- To discuss the outcomes of AIE patients in relation to the pandemic.
- To highlight aspects requiring further investigation regarding AIE management and outcomes post-discharge.
Main Methods:
- Review and commentary on existing literature regarding AIE during the COVID-19 pandemic.
- Analysis of patient profiles and hospital admission features.
- Comparison of outcomes between pandemic and pre-pandemic AIE cases.
Main Results:
- Patients with AIE during the pandemic presented with higher-risk features.
- Despite challenging operations, AIE patients during the pandemic did not experience worse outcomes compared to pre-pandemic cohorts.
- The study emphasizes the need for further investigation into hospital management and post-discharge outcomes.
Conclusions:
- Hospital management and patient profiles for acute cardiovascular syndromes, including AIE, were significantly affected by the COVID-19 pandemic.
- While AIE patients during the pandemic showed higher-risk indicators, their outcomes were comparable to pre-pandemic levels.
- Further research is warranted to fully understand and optimize hospital management and post-discharge care for AIE patients in the context of pandemics.
Abstract:
The COVID-19 pandemic has remarkably impacted the hospital management and the profile of patients suffering from acute cardiovascular syndromes. Among them, acute infective endocarditis (AIE) represented a rather frequent part of these urgent/emergent procedures. The paper by Liu et al. has clearly shown the higher risk features which patients with a diagnosis of AIE presented at hospital admission during the first part (first and second waves) of the outbreak, often requiring challenging operations, but fortunately not associated with the worse outcome if compared to results obtained before the SARS-2 pandemic. The report discussed herein presents several other aspects worth discussion and comments, particularly in relation to hospital management and postdischarge outcome which certainly deserve to be highlighted, but also further investigations.
Related Concept Videos
Endocarditis I: Introduction
Endocarditis II: Clinical Features of Infective Endocarditis
Endocarditis IV: Nursing Management
Endocarditis III: Medical Management
Myocarditis III: Medical Management
Myocarditis II: Clinical Features and Diagnostic Tests

