Acute infective endocarditis during COVID-19 pandemic time: The dark side of the moon

Roberto Lorusso1,2, Antonio M Calafiore3, Michele Di Mauro1

  • 1Cardio-Thoracic Surgery Department, Heart and Vascular Centre, Maastricht University Medical Centre, Maastricht, The Netherlands.

Insights

The COVID-19 pandemic impacted acute cardiovascular syndromes, including acute infective endocarditis (AIE). Patients with AIE during the pandemic faced higher risks but had similar outcomes to pre-pandemic patients.

Area of Science:

  • Cardiology
  • Infectious Diseases
  • Hospital Management

Background:

  • The COVID-19 pandemic significantly altered hospital management and patient demographics for acute cardiovascular syndromes.
  • Acute infective endocarditis (AIE) emerged as a frequent condition necessitating urgent surgical procedures during the pandemic.
  • Previous research indicated higher-risk features in AIE patients during early pandemic waves.

Purpose of the Study:

  • To comment on hospital management strategies for AIE patients during the COVID-19 pandemic.
  • To discuss the outcomes of AIE patients in relation to the pandemic.
  • To highlight aspects requiring further investigation regarding AIE management and outcomes post-discharge.

Main Methods:

  • Review and commentary on existing literature regarding AIE during the COVID-19 pandemic.
  • Analysis of patient profiles and hospital admission features.
  • Comparison of outcomes between pandemic and pre-pandemic AIE cases.

Main Results:

  • Patients with AIE during the pandemic presented with higher-risk features.
  • Despite challenging operations, AIE patients during the pandemic did not experience worse outcomes compared to pre-pandemic cohorts.
  • The study emphasizes the need for further investigation into hospital management and post-discharge outcomes.

Conclusions:

  • Hospital management and patient profiles for acute cardiovascular syndromes, including AIE, were significantly affected by the COVID-19 pandemic.
  • While AIE patients during the pandemic showed higher-risk indicators, their outcomes were comparable to pre-pandemic levels.
  • Further research is warranted to fully understand and optimize hospital management and post-discharge care for AIE patients in the context of pandemics.

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