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Updated: Oct 4, 2025

Accessing the Cytotoxicity and Cell Response to Biomaterials
Published on: July 8, 2021
[Bioactive materials in conservative dentistry]
Phoebe Burrer1, Thomas Attin1, Matej Par1,2
1Klinik für Zahnerhaltung und Präventivzahnmedizin, Zentrum für Zahnmedizin der Universität Zürich, Zürich, Schweiz.
Bioactive glass particles enhance dental composites with remineralizing and antibacterial effects. Further research is needed to optimize these bioactive composites for biomimetic dental restorations.
Area of Science:
- Biomaterials Science
- Dental Materials Science
- Nanotechnology
Background:
- Bioactive glass particles are increasingly used in dental restorative materials.
- These particles offer promising remineralizing effects on dental hard tissues.
- Antibacterial properties are also a key advantage of bioactive glass fillers.
Purpose of the Study:
- To review the incorporation of bioactive glass particles in dental restorative materials.
- To highlight the remineralizing and antibacterial potential of these composites.
- To identify areas for further research in biomimetic restorative dentistry.
Main Methods:
- Literature review of studies on bioactive glass in dental composites.
- Analysis of reported remineralizing and antibacterial properties.
- Evaluation of current market availability and future research directions.
Main Results:
- Bioactive glass incorporation has demonstrated positive effects on dental hard tissues.
- The antibacterial activity of these composites is a significant benefit.
- Several bioactive filler-doped materials are currently available.
Conclusions:
- Bioactive glass composites show significant promise for dental restorations.
- Further research is essential to optimize these materials for biomimetic applications.
- Tailoring bioactive composites is key to advancing restorative dentistry.
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