Recent Advances in Bioorthogonal Click Chemistry for Biomedical Applications.

Area of Science:

• Biomaterials Science
• Chemical Biology
• Regenerative Medicine

Background:

• Bioorthogonal click chemistry offers selective and biocompatible reactions, ideal for advanced biomaterial design.
• It has become a key tool in tissue engineering and regenerative medicine since the early 2000s.

Purpose of the Study:

• To review recent advancements in bioorthogonal click chemistry for biomaterials.
• To highlight applications in 3D scaffolds, cell encapsulation, drug delivery, imaging, and cell therapy.

Main Methods:

• Review of recent literature on bioorthogonal click chemistry in biomaterial development.
• Analysis of applications in tissue engineering, regenerative medicine, and biomedical fields.

Main Results:

• Bioorthogonal click chemistry facilitates the creation of advanced 3D biocompatible scaffolds.
• It enables the development of cell-encapsulated biomaterials for various biomedical applications.

Conclusions:

• Bioorthogonal click chemistry is a powerful platform for next-generation biomaterials.
• Its versatility supports innovations in drug delivery, imaging, and cell therapy.