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Updated: Oct 4, 2025

Development and Functionalization of Electrolyte-Gated Graphene Field-Effect Transistor for Biomarker Detection
Published on: February 1, 2022
Exploring graphene oxide intrinsic electroactivity to elucidate the non-covalent interactions with DNA
Yaquan Liang1, Wei Li Ang1, Rachel Rui Xia Lim1
1Division of Chemistry & Biological Chemistry, School of Physical and Mathematical Sciences, Nanyang Technological University, Singapore 637371, Singapore. a.bonanni@ntu.edu.sg.
Abstract:
We show here how the electrochemical reduction signal of graphene oxide nanocolloids is inhibited upon the formation of non-covalent interactions with single stranded DNA oligonucleotides. The drop in the reduction current intensity is strongly influenced by the nucleobase sequence, and can therefore be directly correlated to the specific DNA homo-oligonucleotide.

