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Related Experiment Video

Updated: Oct 4, 2025

Enucleation of the Prostate for the Treatment of Benign Prostatic Hyperplasia Using a 980 nm Diode Laser
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Enucleation of the Prostate for the Treatment of Benign Prostatic Hyperplasia Using a 980 nm Diode Laser

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Real-world data comparing minimally invasive surgeries for benign prostatic hyperplasia.

Brendan L Raizenne1, Xinyan Zheng2, Jialin Mao2

  • 1Division of Urology, Centre Hospitalier de l'Université de Montréal, Montreal, QC, Canada.

World Journal of Urology
|February 2, 2022
PubMed
Summary

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Prostatic urethral lift (PUL) shows comparable reoperation rates to older thermal therapies for benign prostatic hyperplasia (BPH). This study found similar long-term risks of reoperation and stricture development between PUL and transurethral microwave therapy or transurethral needle ablation.

Area of Science:

  • Urology
  • Minimally Invasive Surgery
  • Health Outcomes Research

Background:

  • Benign prostatic hyperplasia (BPH) is a common condition in aging men.
  • Surgical interventions aim to alleviate lower urinary tract symptoms.
  • Thermal energy procedures and prostatic urethral lift (PUL) are established BPH treatments.

Purpose of the Study:

  • To compare surgical outcomes between prostatic urethral lift (PUL) and traditional thermal energy procedures for BPH.
  • To evaluate short-term and long-term efficacy and safety profiles.
  • To inform clinical decision-making for BPH management.

Main Methods:

  • An observational, population-based study included 2694 men with BPH.
  • Data were collected from New York State and California between 2005 and 2018.
Keywords:
Benign prostatic hyperplasiaMinimally invasive surgeriesProstatic urethral liftReal-world dataThermal energy procedures

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  • Statistical analyses included Chi-square tests, logistic regressions, Kaplan-Meier curves, and Cox regressions.

    • Main Results:

    • PUL demonstrated low 30-day and 90-day inpatient or ER readmission rates.
    • No significant differences in 1- and 3-year reoperation risks were found between PUL, TUNA, and TUMT.
    • The risks of stricture development at 1 and 3 years for PUL were very low (0.2%).

    Conclusions:

    • Prostatic urethral lift (PUL) shows comparable 1- and 3-year reoperation risks to thermal energy procedures for BPH.
    • Short-term readmission rates for PUL were favorable, except for 90-day ER readmissions.
    • PUL is a viable alternative with similar long-term outcomes to older thermal therapies.