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Cardiovascular risk factors associated with coronary ectasia and acute myocardial infarction

Eduardo Rojas-Milán1, Cristina E Morales-de León2, Andrés García-Rincón3

  • 1Internal Medicine Department, Specialty Hospital, Centro Médico Nacional La Raza, Mexico City.

Gaceta Medica De Mexico
|February 2, 2022
PubMed

Insights

Coronary ectasia, a condition affecting blood vessels in the heart, was found in 8.5% of patients with acute myocardial infarction. Key risk factors include hypercholesterolemia and herbicide exposure.

Area of Science:

  • Cardiology
  • Vascular Biology
  • Epidemiology

Background:

  • Coronary ectasia is rare and may have distinct risk factors from coronary artery disease.
  • Understanding its prevalence in acute myocardial infarction (AMI) is crucial.

Purpose of the Study:

  • To determine the prevalence of coronary ectasia in patients presenting with AMI.
  • To identify associated cardiovascular risk factors (CVRFs) and biomarkers in these patients.

Main Methods:

  • Retrospective, cross-sectional study of 3,254 cardiac catheterizations for AMI.
  • Included 558 patients with coronary ectasia and controls, analyzing recorded CVRFs.
  • Employed descriptive statistics, bivariate and multivariate analysis, calculating odds ratios (OR).

Main Results:

  • Prevalence of coronary ectasia was 8.5% among AMI patients.
  • Elevated platelet/lymphocyte ratio (PLR) observed in patients with ectasia (p=0.003).
  • Multivariate analysis identified hypercholesterolemia (OR: 3.90) and herbicide exposure (OR: 6.82) as significant risk factors.

Conclusions:

  • A notable prevalence of coronary ectasia (8.5%) was identified in AMI patients.
  • Hypercholesterolemia and herbicide exposure are significant risk factors for coronary ectasia.
  • Elevated PLR suggests potential inflammatory involvement; early detection is vital due to links with acute coronary events.
Abstract

Keywords:
AngiografíaAngiographyCoronary artery diseaseEnfermedad coronariaHerbicidasHerbicidesInfarto de miocardioMyocardial infarctionPrevalencePrevalencia

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