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Epilepsy and Seizures: Overview

Epilepsy and Seizures: Overview

Epilepsy is a chronic neurological disease marked by recurrent, unpredictable seizures. These seizures are caused by abnormal electrical discharges in the brain, leading to behavior, sensation, or consciousness alterations. They can also cause transient impairment of awareness, interfering with daily activities.
Various factors can trigger epilepsy, including genetic factors, brain damage, metabolic causes, and unknown etiology. Diagnosis of epilepsy involves electroencephalography (EEG), which...

Seizures: Classification

Seizures: Classification

Epilepsy is primarily characterized by unpredictable seizures, either provoked by an identifiable factor, such as injury or illness, or unprovoked, occurring spontaneously without apparent cause.
Seizures are typically classified into two main categories: focal and generalized seizures.
Focal Seizures
Focal seizures originate from specific regions of the brain. These seizures are further sub-classified into two types:

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Related Experiment Video

Updated: Oct 4, 2025

Author Spotlight: Unraveling Seizure Dynamics and Novel Therapeutics for Status Epilepticus Using CMOS High-Density Microelectrode Array Systems

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Epilepsy With Suicide: A Bibliometrics Study and Visualization Analysis via CiteSpace.

Yi Guo^1,2, Zheng-Yan-Ran Xu², Meng-Ting Cai²

¹Department of General Practice and International Medicine, School of Medicine, Second Affiliated Hospital, Zhejiang University, Hangzhou, China.

Frontiers in Neurology

|February 3, 2022

Summary

This study analyzed epilepsy and suicide research, revealing key trends like depression, antiseizure medications, and pediatric epilepsy as critical factors. Future research should focus on psychiatric comorbidities and suicide risks in epilepsy patients.

Keywords:

CiteSpace bibliometrics epilepsy suicide visualization analysis

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Published on: October 19, 2021

Area of Science:

Bibliometrics
Neuroscience
Public Health

Background:

Epilepsy is a chronic neurological disorder associated with increased suicide risk.
Understanding research trends is crucial for addressing suicide in epilepsy patients.

Purpose of the Study:

To analyze the research landscape of epilepsy and suicide.
To identify current hotspots and future frontiers in this research area using bibliometric analysis.

Main Methods:

A systematic search of the Web of Science Core Collection (WoSCC) was conducted.
CiteSpace software was employed to visualize collaboration networks and identify research trends.
Data analysis covered publications from inception to September 30, 2021.

Main Results:

631 publications on epilepsy and suicide were identified.
The USA led in publications, with Columbia University as the top institution.
Key research topics included depression, antiseizure medications, pediatric epilepsy, and suicide risk factors in patients with epilepsy (PWEs).

Conclusions:

Active international and institutional collaboration exists in epilepsy suicide research.
Emerging trends highlight the impact of depression, antiseizure medications, and pediatric epilepsy on suicide.
Future research should prioritize psychiatric comorbidities, suicidal tendencies in PWEs, and rational antiseizure medication use.