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Published on: July 24, 2013
The Prevalence and Associated Factors of Hypertension among HIV Patients
Grace Wambura Mbuthia1, Karani Magutah2, Stephen T McGarvey3
1College of Health Sciences, Jomo Kenyatta University of Agriculture and Technology, P.O. Box 62000- 0200, Nairobi, Kenya.
Insights
Hypertension is prevalent in Human Immunodeficiency Virus (HIV) patients in Kenya, with risk factors including age over 40, male sex, alcohol use, and obesity. Antiretroviral therapy did not influence hypertension rates.
Area of Science:
- Public Health
- Infectious Diseases
- Cardiology
Background:
- Sub-Saharan Africa faces a dual burden of cardiovascular diseases (CVD) and Human Immunodeficiency Virus (HIV).
- Individuals with HIV have a 1.5-2 times higher risk of developing CVD risk factors.
- Hypertension is a significant driver of the escalating CVD epidemic in SSA, yet its prevalence among HIV patients in Kenya remains under-documented.
Purpose of the Study:
- To determine the prevalence of hypertension among HIV patients receiving care at Thika Level 5 Hospital Comprehensive Care Clinic (CCC) in Nairobi, Kenya.
- To identify factors associated with hypertension in this patient population.
Main Methods:
- A cross-sectional study involving a review of patient records from the Thika Level 5 Hospital CCC.
- Included adult patients seen within the last six months.
- Hypertension defined as SBP ≥140 mmHg or DBP ≥90 mmHg on two separate readings; overweight/obesity defined as BMI ≥25 kg/m².
Main Results:
- Out of 939 HIV patients, 68.8% were female. The median age was 44 years.
- Hypertension prevalence was higher in males (25.3%) than females (16.9%).
- Factors associated with hypertension included age >40 years (AOR=2.80), male sex (AOR=2.10), alcohol consumption (AOR=2.56), and overweight/obesity (AOR=2.77). Antiretroviral therapy regimen and duration showed no association.
Conclusions:
- A high prevalence of hypertension exists among HIV patients in Kenya.
- Traditional cardiovascular risk factors, not ART specifics, are linked to hypertension in this group.
- Integrating hypertension management into routine HIV care is crucial.
Background:
The dual burden of cardiovascular diseases and Human Immunodeficiency Virus (HIV) in sub-Saharan Africa is of public health concern. Persons living with HIV are 1.5-2 times more likely to develop CVD risk factors compared to the noninfected individuals. Hypertension is a major risk factor leading to the rising CVD epidemic in SSA. However, the burden of hypertension among HIV patients in Kenya is not well documented.
Objective:
This study determined the prevalence and the associated factors of hypertension among HIV patients receiving regular care at Thika Level 5 Hospital Comprehensive Care Clinic (CCC), within metropolitan Nairobi, Kenya.
Methods:
The current cross-sectional study involved review of patients' records/charts. Charts for adult patients seen in the last 6 months at Thika Level 5 Hospital CCC were included in the study. Hypertension was defined as systolic blood pressure ≥140 mmHg and/or diastolic blood pressure ≥90 mmHg on two different readings one month apart, while overweight/obesity was defined as body mass index (BMI) ≥ 25 kg/m2.
Results:
In a sample of 939 HIV patients, the majority, 68.8% (646), were female. The patients' ages ranged from 18 to 84 years with a median age of 44 (IQR 37-51) years. The mean BMI was higher for females (25.8 kg/m2) compared to that of males (23.1 kg/m2). However, the prevalence of hypertension was higher among males (25.3%) compared to females (16.9%). Age >40 years (AOR = 2.80, p ≤ 0.001), male sex (AOR = 2.10; p=0.04), history of alcohol consumption (AOR = 2.56, p ≤ 0.001), and being overweight/obese (AOR = 2.77 p ≤ 0.001) were significantly associated with hypertension. The antiretroviral (ARV) regimen and, additionally, the duration of antiretroviral therapy had no association with being hypertensive.
Conclusion:
The prevalence of hypertension is high among HIV patients. Traditional cardiovascular risk factors were associated with hypertension, but no association was observed with ART regime or duration of ARV use. There is a need to integrate hypertension management into regular HIV care.
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