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Updated: Oct 4, 2025

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Published on: January 17, 2025
Recurrent Silicone Embolism Syndrome requiring VA ECMO
Nikhil Madan1, Umair Khan2, Anthony Martins3
1Division of Pulmonary and Critical Care Medicine, Department of Medicine, Newark Beth Israel Medical Center, Newark, NJ, 07112, USA.
Illegal silicone injections can cause Silicone Embolism Syndrome (SES), a severe lung and heart condition. This case highlights the dangers of illicit procedures, even when repeated by the same patient.
Area of Science:
- Medical Science
- Toxicology
Background:
- The illegal use of liquid silicone for cosmetic procedures is increasing.
- Silicone, once considered inert, is now linked to inflammatory complications like Silicone Embolism Syndrome (SES).
Observation:
- A patient developed SES after unlicensed gluteal augmentation with liquid silicone.
- The patient required veno-arterial extracorporeal membrane oxygenation due to acute respiratory distress and cardiopulmonary failure.
- This marks the first reported case of the same patient experiencing SES twice after separate illicit silicone injections.
Findings:
- SES is a critical complication of unlicensed liquid silicone injections, leading to severe respiratory and cardiopulmonary compromise.
- Recurrence of SES in the same patient underscores the persistent risks associated with illicit cosmetic procedures.
Implications:
- There is a critical need for public education on the dangers of non-medical grade silicone and illicit body modifications.
- Healthcare providers must be vigilant in recognizing SES symptoms and consider the possibility of repeat illicit injections.
- The proliferation of counterfeit silicone products suggests a continued rise in SES cases, necessitating proactive medical and public health strategies.
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Acute Respiratory Failure-III

