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Correction to: Identification of the Specific Causes of Polysorbate 20 Degradation in Monoclonal Antibody

Sisi Zhang1, Caterina Riccardi2, Douglas Kamen2

  • 1Analytical Chemistry, Regeneron Pharmaceuticals, Tarrytown, NY, 10591, USA.

Pharmaceutical Research
|February 3, 2022
PubMed
Abstract

No abstract available in PubMed .

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Polymorphism refers to the existence of a drug substance in multiple crystalline forms, known as polymorphs. Recently, this term has been expanded to include solvates (forms containing a solvent), amorphous forms (non-crystalline forms), and desolvated solvates (forms from which the solvent has been removed).
Some polymorphic crystals possess lower aqueous solubility than their amorphous counterparts, leading to incomplete absorption. For instance, the oral suspension of Chloramphenicol, which...
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