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Sleep quality, stress and thyroid cancer: a case-control study
S Afrashteh1, M Fararouei2, M T Parad1
1Student Research Committee, Shiraz University of Medical Sciences, Shiraz, Iran.
Journal of Endocrinological Investigation
|February 3, 2022
Summary
High stress and short temper increase thyroid cancer risk, while good sleep quality is protective. These factors may be targets for cancer prevention strategies.
Area of Science:
- Oncology
- Epidemiology
- Psychology
Background:
- Stress and poor sleep are linked to adverse health outcomes, including cancer.
- The relationship between psychological factors and thyroid cancer (TC) risk requires further investigation.
Purpose of the Study:
- To assess the association between sleep quality, short-temperedness, and stress levels with the risk of developing thyroid cancer.
Main Methods:
- A case-control study involving 361 newly diagnosed thyroid cancer patients and 347 matched controls.
- Multiple logistic regression analysis was employed to examine the associations between TC risk and psychological factors.
Main Results:
- Increased stress (OR=3.07) and short-temperedness (OR=2.00) were significantly associated with a higher risk of thyroid cancer.
- Good sleep quality demonstrated a protective effect, reducing the risk of thyroid cancer (OR=0.36 and OR=0.45).
Conclusions:
- Interventions aimed at reducing stress and improving sleep quality may play a role in thyroid cancer prevention.
- Further research is warranted to validate these findings and explore their implications for public health strategies.
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