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Comparative Proteomic Analysis of Whole Kidney, Medulla, and Cortical Tubules in Diabetic Pathogenesis of Kidney Injury in Mice
Published on: May 2, 2025
Diabetic myonecrosis in end-stage renal disease
Mohit Naredi1, Navneet Adhikari2, Gaurav Prakash Bhardwaj2
1Department of Nephrology, Pushpawati Singhania Research Institute, Press Enclave Road, Sheikh Sarai Phase 1, New Delhi 110017, India.
Abstract:
Diabetic myonecrosis or muscle infarction (DMI), a clinicoradiological entity is an underdiagnosed complication of diabetes mellitus. It refers to spontaneous aseptic necrosis of skeletal muscles commonly of the lower limb without evidence of any large vessel disease. It presents as painful swollen limb without any external insult in patients with long-standing diabetes mellitus with other microvascular complications especially nephropathy. We present four instances of DMI in our patients who had end-stage renal disease with a varied course.
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