Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Visual noise in augmented reality improves vision in age-related macular degeneration.

npj aging·2026
Same author

Reflections on the Safety and Stability of the Second-Generation Suprachoroidal Retinal Prosthesis: Response.

Clinical & experimental ophthalmology·2026
Same author

Objective perimetry and diabetic retinopathy progression: a 10-year follow-up study.

Frontiers in endocrinology·2026
Same author

Clinical profile and associated risk factors of diabetic retinopathy at a tertiary eye center in Brunei Darussalam.

Taiwan journal of ophthalmology·2026
Same author

Internal Limiting Membrane Flap Versus Conventional Peeling for Idiopathic Full Thickness Macular Holes: A Registry Analysis of 2990 Eyes.

Clinical & experimental ophthalmology·2025
Same author

Inherited Retinal Disease or Age-Related Macular Degeneration: Predictive Value of Genetic Testing in Macular Disease With Atypical Atrophy.

Clinical & experimental ophthalmology·2025
Same journal

Balance Performance in People With Peripheral Visual Field Loss: A Systematic Review and Meta-Analysis.

Translational vision science & technology·2026
Same journal

In Vivo Confocal Microscopy Revealed Alteration of Limbal Stem Cells and Sub-Basal Nerve Plexus in Allergic and Dry Eye-Related Ocular Surface Diseases.

Translational vision science & technology·2026
Same journal

Comparison of Measurement Techniques for Photoreceptor Loss in Geographic Atrophy.

Translational vision science & technology·2026
Same journal

Deep Learning-Based Automated Segmentation and Multi-Parametric Quantitative Assessment of the Lacrimal Drainage System on CT-DCG.

Translational vision science & technology·2026
Same journal

Tear Fluid Lymphotoxin-Alpha as a Diagnostic Biomarker for the Stratification of Dry Eye Disease.

Translational vision science & technology·2026
Same journal

Advancing Retinal Vessel Analysis: Reproducibility of Myogenic Constriction and Assessment of Regulatory Capacity.

Translational vision science & technology·2026
See all related articles

Related Experiment Video

Updated: Oct 4, 2025

Dynamic Visual Tests to Identify and Quantify Visual Damage and Repair Following Demyelination in Optic Neuritis Patients
12:23

Dynamic Visual Tests to Identify and Quantify Visual Damage and Repair Following Demyelination in Optic Neuritis Patients

Published on: April 14, 2014

14.2K

Clustered Volleys Stimulus Presentation for Multifocal Objective Perimetry.

Corinne F Carle1, Andrew C James1, Faran Sabeti1,2

  • 1John Curtin School of Medical Research, Australian National University, Canberra, Australia.

Translational Vision Science & Technology
|February 3, 2022
PubMed
Summary
This summary is machine-generated.

The new Clustered Volleys (CVs) method for multifocal pupillographic objective perimetry (mfPOP) significantly improves signal quality and diagnostic accuracy compared to the original Continuous stimulus presentation. This advancement allows for shorter, more efficient mfPOP tests.

More Related Videos

Stimulus-specific Cortical Visual Evoked Potential Morphological Patterns
09:42

Stimulus-specific Cortical Visual Evoked Potential Morphological Patterns

Published on: May 12, 2019

6.1K
Assessing Binocular Central Visual Field and Binocular Eye Movements in a Dichoptic Viewing Condition
07:45

Assessing Binocular Central Visual Field and Binocular Eye Movements in a Dichoptic Viewing Condition

Published on: July 21, 2020

4.6K

Related Experiment Videos

Last Updated: Oct 4, 2025

Dynamic Visual Tests to Identify and Quantify Visual Damage and Repair Following Demyelination in Optic Neuritis Patients
12:23

Dynamic Visual Tests to Identify and Quantify Visual Damage and Repair Following Demyelination in Optic Neuritis Patients

Published on: April 14, 2014

14.2K
Stimulus-specific Cortical Visual Evoked Potential Morphological Patterns
09:42

Stimulus-specific Cortical Visual Evoked Potential Morphological Patterns

Published on: May 12, 2019

6.1K
Assessing Binocular Central Visual Field and Binocular Eye Movements in a Dichoptic Viewing Condition
07:45

Assessing Binocular Central Visual Field and Binocular Eye Movements in a Dichoptic Viewing Condition

Published on: July 21, 2020

4.6K

Area of Science:

  • Ophthalmology
  • Neuroscience
  • Medical Technology

Background:

  • Multifocal pupillographic objective perimetry (mfPOP) is an emerging tool for diagnosing visual and neurological disorders.
  • Current mfPOP methods use a sparse Continuous stimulus presentation, which may be limited by signal quality.
  • Optimizing mfPOP signal quality is crucial for improving diagnostic capabilities.

Purpose of the Study:

  • To compare the signal quality of the original mfPOP Continuous stimulus presentation with a novel Clustered Volleys (CVs) method.
  • To evaluate differences in signal-to-noise ratios (SNRs) between the two mfPOP presentation methods in normal subjects.
  • To test the hypothesis that CVs method enhances SNRs due to pupillary gain stabilization.

Main Methods:

  • Data from six studies comparing original and CVs mfPOP methods were analyzed.
  • 440 tests from 96 normal subjects were included, with tests lasting 6 minutes each.
  • Per-region SNRs and goodness-of-fit (r2) were compared between the Continuous and CVs mfPOP methods.

Main Results:

  • CVs mfPOP variants showed 35-57% higher mean SNRs than the original method (P < 0.001 in five studies).
  • Goodness-of-fit (r2) increased 2.3-3.4 fold with the CVs method (all P < 0.001).
  • Significant SNR improvements were observed across all test regions and in 98% of subjects.

Conclusions:

  • The CVs mfPOP stimulus presentation method significantly enhances signal quality over the original Continuous method.
  • Improved pupillary gain stabilization during CVs presentation likely underlies the enhanced signal quality.
  • These advancements in mfPOP signal quality improve diagnostic accuracy and enable shorter test durations.