Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Protein Dynamics in Living Cells

Protein Dynamics in Living Cells

Different fluorescence-based techniques are used to study the protein dynamics in living cells. These techniques include FRAP, FRET, and PET.
Fluorescent recovery after photobleaching (FRAP) is a fluorescent-protein-based detection technique used to quantify protein movement rates within the cell. This method exposes a small portion of the cell to an intense laser beam. The laser beam causes permanent photobleaching of the fluorophore-tagged proteins in the exposed region. As the bleached...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Membrane Protein Folding and Biogenesis: Insights from Single-Molecule Force Spectroscopy.

Chemical reviews·2026

Same author

Exocyst stimulates multiple steps of exocytic SNARE complex assembly and vesicle fusion.

Nature structural & molecular biology·2024

Same author

Profiling protein-protein interactions to predict the efficacy of B-cell-lymphoma-2-homology-3 mimetics for acute myeloid leukaemia.

Nature biomedical engineering·2024

Same author

Profiling of BCLxL Protein Complexes in Non-Small Cell Lung Cancer Cells via Multiplexed Single-Molecule Pull-Down and Co-Immunoprecipitation.

Analytical chemistry·2024

Same author

The New Kid on the Block: Mass Photometry.

Molecules and cells·2023

Same author

Enantioselective sensing by collective circular dichroism.

Nature·2022

Same journal

Oxidative stress drives liver failure during in vivo partial reprogramming.

Molecules and cells·2026

Same journal

scpp5 regulates tooth development and injury-induced repair in zebrafish through mineralization and Wnt/β-catenin signaling.

Molecules and cells·2026

Same journal

Corrigendum to "Molecular role of developmentally regulated GTP-binding protein 1 in coordinating osteoclast and osteoblast differentiation during bone remodeling" [Mol. Cells 49 (2026) 100342].

Molecules and cells·2026

Same journal

Multiple ShKT domain-containing MUL-1 proteins act as redox-responsive modulators of oxidative stress signaling in C. elegans.

Molecules and cells·2026

Same journal

Small molecule inhibition of voltage dependent anion channel 1 reroutes mitochondrial metabolite flux.

Molecules and cells·2026

Same journal

Adherent-to-suspension transition modulates circulating tumor cell dynamics and metastatic potential in melanoma.

Molecules and cells·2026

See all related articles

Search research articles

Related Experiment Video

Updated: Oct 4, 2025

Integrative Toolkit to Analyze Cellular Signals: Forces, Motion, Morphology, and Fluorescence

Integrative Toolkit to Analyze Cellular Signals: Forces, Motion, Morphology, and Fluorescence

Published on: March 5, 2022

Emerging Biophysics Tools for Biologists

Tae-Young Yoon^1,2

¹School of Biological Sciences, Seoul National University, Seoul 08826, Korea.

Molecules and Cells

|February 3, 2022

Summary

No abstract available in PubMed .

More Related Videos

All-optical Mechanobiology Interrogation of Yes-associated Protein in Human Cancer and Normal Cells using a Multi-functional System

All-optical Mechanobiology Interrogation of Yes-associated Protein in Human Cancer and Normal Cells using a Multi-functional System

Published on: December 20, 2021

BioMEMS: Forging New Collaborations Between Biologists and Engineers

BioMEMS: Forging New Collaborations Between Biologists and Engineers

Published on: November 1, 2007

Related Experiment Videos

Last Updated: Oct 4, 2025

Integrative Toolkit to Analyze Cellular Signals: Forces, Motion, Morphology, and Fluorescence

Integrative Toolkit to Analyze Cellular Signals: Forces, Motion, Morphology, and Fluorescence

Published on: March 5, 2022

All-optical Mechanobiology Interrogation of Yes-associated Protein in Human Cancer and Normal Cells using a Multi-functional System

All-optical Mechanobiology Interrogation of Yes-associated Protein in Human Cancer and Normal Cells using a Multi-functional System

Published on: December 20, 2021

BioMEMS: Forging New Collaborations Between Biologists and Engineers

BioMEMS: Forging New Collaborations Between Biologists and Engineers

Published on: November 1, 2007