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Tumor Progression

Tumor Progression

Tumor progression is a phenomenon where the pre-formed tumor acquires successive mutations to become clinically more aggressive and malignant. In the 1950s, Foulds first described the stepwise progression of cancer cells through successive stages.
Colon cancer is one of the best-documented examples of tumor progression. Early mutation in the APC gene in colon cells causes a small growth on the colon wall called a polyp. With time, this polyp grows into a benign, pre-cancerous tumor. Further...

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Updated: Oct 4, 2025

Translational Orthotopic Models of Glioblastoma Multiforme

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Published on: February 17, 2023

Pseudoprogression in low-grade glioma

Jason M Slater¹, Helen A Shih¹

¹Department of Radiation Oncology, Massachusetts General Hospital, Boston, MA, USA.

Translational Cancer Research

|February 4, 2022

Summary

No abstract available in PubMed .

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