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Updated: Oct 4, 2025

Identification of Intracellular Signaling Events Induced in Viable Cells by Interaction with Neighboring Cells Undergoing Apoptotic Cell Death
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Identification of Intracellular Signaling Events Induced in Viable Cells by Interaction with Neighboring Cells Undergoing Apoptotic Cell Death

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A feedback circuit of miR-34a/MDM4/p53 regulates apoptosis in chronic lymphocytic leukemia cells

Lei Cao1, Yun Liu1,2, Jin-Bo Lu1

  • 1Department of Hematology, the First Affiliated Hospital of Nanjing Medical University, Jiangsu Province Hospital, Collaborative Innovation Center for Cancer Personalized Medicine, Nanjing, China.

Translational Cancer Research
|February 4, 2022
PubMed
Abstract

Keywords:
Chronic lymphocytic leukemia (CLL)murine double minute 4 (MDM4), miR-34a, modulating mechanisms, p53

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