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Related Experiment Video

Updated: Oct 4, 2025

Clinical Application of Single-Surgeon, Three-Port, Laparoscopic Resection for Colorectal Cancer with Natural Orifice Specimen Extraction
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Rectal clear cell sarcoma-a case report.

Chenguang Bai1, Min Dong1, Wenrong Shen1

  • 1Departments of Radiology, Jiangsu Cancer Hospital, Jiangsu Institute of Cancer Research, Nanjing Medical University Affiliated Cancer Hospital, Nanjing, China.

Translational Cancer Research
|February 4, 2022
PubMed
Summary
This summary is machine-generated.

Gastrointestinal clear cell sarcomas (GICCSs) are rare, aggressive tumors. Early detection using CT and MRI is crucial for diagnosis and treatment, as immunotherapy showed limited efficacy in this case.

Keywords:
Gastrointestinal clear cell sarcomas (GICCS)case reportenergy spectrum computed tomography (energy spectrum CT)rectum

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Area of Science:

  • Oncology
  • Gastroenterology
  • Radiology

Background:

  • Gastrointestinal clear cell sarcomas (GICCSs) are rare malignant mesenchymal tumors.
  • They typically occur in the ileum or rectum and are highly invasive.
  • Metastasis via lymphatic or bloodstream is common at diagnosis.

Observation:

  • A patient presented with a gastric fundus mass, later confirmed as rectal clear cell sarcoma.
  • CT and MRI revealed widespread metastases in lymph nodes, lungs, liver, and bone.
  • Energy spectrum CT confirmed the gastric and rectal lesions were consistent.

Findings:

  • The case presented as either multiple GICCSs or rectal GICCS with gastric metastasis.
  • The patient experienced rapid deterioration and died due to liver dysfunction after immunotherapy.
  • Current treatments like surgery, radiotherapy, and chemotherapy have limited effectiveness.

Implications:

  • Early detection and accurate diagnosis of GICCS are critical.
  • CT and MRI play essential roles in identifying and characterizing these tumors.
  • Further research is needed to improve GICCS treatment strategies.