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Lung adenocarcinoma initially mimicking localized emphysema
Jiahan Cheng1,2, Jiandong Mei1,2, Qiang Pu1,2
1Department of Thoracic Surgery, West China Hospital, Sichuan University, Chengdu 610041, China.
Translational Cancer Research
|February 4, 2022
Summary
This case study highlights a rare instance of lung cancer initially misdiagnosed as emphysema. Continuous monitoring is crucial as slow-growing lesions may represent malignant transformation in high-risk individuals.
Area of Science:
- Pulmonology
- Oncology
- Radiology
Background:
- Lung cancer diagnosis can be challenging, especially with slow-growing lesions.
- Radiographic features can evolve over time, mimicking benign conditions like emphysema.
Observation:
- A patient presented with radiographic changes over five years initially interpreted as localized emphysema.
- The lesion progressively transformed, ultimately revealing characteristics of a solid malignant nodule.
Findings:
- The nodule was confirmed as adenocarcinoma after thoracoscopic left upper lobectomy and lymphadenectomy.
- This case exemplifies the potential for slow-growing emphysema-like lesions to undergo malignant transformation.
Implications:
- Emphasizes the need for prolonged, close radiographic monitoring of localized emphysema in high-risk patients.
- Suggests that persistent or evolving radiographic abnormalities, even if initially benign-appearing, warrant thorough investigation for lung cancer.
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