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Signal Sequences and Sorting Receptors

Signal Sequences and Sorting Receptors

Signal sequences are short amino acid sequences that guide newly synthesized proteins to their proper location within the cell. Classical signal sequences are fifteen to sixty amino acids long and present at the N-terminus of a polypeptide chain. Each signal sequence has a conserved segment of basic residues towards their N terminus, a hydrophobic core, and a C-terminus rich in polar residues. The C-terminus also contains a signal cleavage site and features a -3 -1 sequence motif. The -3-1...

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Related Experiment Video

Updated: Oct 4, 2025

Extracellular Protein Microarray Technology for High Throughput Detection of Low Affinity Receptor-Ligand Interactions

Extracellular Protein Microarray Technology for High Throughput Detection of Low Affinity Receptor-Ligand Interactions

Published on: January 7, 2019

SPSED: A Signal Peptide Secretion Efficiency Database

Chong Peng^1,2,3,4, Yixue Guo⁴, Shaodong Ren⁴

¹Key Laboratory of Industrial Fermentation Microbiology, Education Ministry of China, Tianjin, China.

Frontiers in Bioengineering and Biotechnology

|February 4, 2022

Summary

No abstract available in PubMed .

Keywords:

bacteria database recombinant protein secretion efficiency signal peptide

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